Evidence map›Paper›PMID 41809230›Full record

ArticleJournal of community hospital internal medicine perspectives2026

Losartan-induced Angioedema: A Case Report and Review of Literature.

Leila C Tou, Audrey Nourse, Rachel Cox, Spencer Stanford

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leila C TouDepartment of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.
Audrey NourseDepartment of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.
Rachel CoxDepartment of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.
Spencer StanfordDepartment of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin receptor blockers (ARBs) are frequently prescribed as alternatives to angiotensin-converting enzyme inhibitors (ACEIs), particularly in patients who experience ACEI-induced adverse effects including cough. Although ARBs are associated with a lower incidence of angioedema, rare cases have been reported in patients without prior ACEI exposure. Here, we describe a 58-year-old Black male who developed lip and facial swelling six months after starting losartan. His symptoms did not improve with antihistamines or corticosteroids but resolved after discontinuation of losartan, which was replaced with amlodipine without recurrence. This case emphasizes the need for clinician awareness of ARB-induced angioedema and the importance of balancing this rare risk against the established cardiovascular and renal benefits of ARB therapy.

Indexed as

ACEIAngioedemaAngiotensin-converting enzyme inhibitorAngiotensin receptor blockerARBBradykinin-induced angioedemaDrug-induced angioedema

Identifiers

PMID41809230
PMCPMC12971131

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.