Evidence map›Paper›PMID 41809716›Full record

ArticleInternational journal of pediatrics2026

Neurodevelopmental Trajectories at 3 Years: Insights From the NASCITA Italian Birth Cohort.

Giulia Segre, Elisa Roberti, Rita Campi, Antonio Clavenna, Maurizio Bonati

Abstract read
In one paragraph

Article in International journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giulia SegreDepartment of Medical Epidemiology, Laboratory of Child Health and Development Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy, marionegri.it.ORCID https://orcid.org/0000-0002-4105-377X
Elisa RobertiDepartment of Medical Epidemiology, Laboratory of Child Health and Development Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy, marionegri.it.ORCID https://orcid.org/0000-0003-3525-9015
Rita CampiDepartment of Medical Epidemiology, Laboratory of Child Health and Development Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy, marionegri.it.ORCID https://orcid.org/0000-0001-8661-6321
Antonio ClavennaDepartment of Medical Epidemiology, Laboratory of Child Health and Development Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy, marionegri.it.ORCID https://orcid.org/0000-0001-5536-4192
Maurizio BonatiDepartment of Medical Epidemiology, Laboratory of Child Health and Development Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy, marionegri.it.ORCID https://orcid.org/0000-0003-3997-3726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Early childhood development is critically influenced by exposure to stressful life events. Identifying children with warning signs (WS) for developmental disorders early is essential for timely intervention. Methods: Family pediatricians evaluated the neurodevelopment of 148 children from the NASCITA cohort using the CDC's Learn the Signs, Act Early Milestones checklist, whereas parents completed the Strengths and Difficulties Questionnaire (SDQ). Univariate and multivariate analyses evaluated associations between WS and maternal characteristics, data concerning pregnancy, delivery and the newborns' health, sleep disturbances and life habits. Results: A total of 14% of children showed WS for developmental disorders at 36 months, a lower percentage than at 24 months (15.8%): for two out of three children, WS disappeared between 24 and 36 months. Persistent WS were noted in 5% of children. Key risk factors identified include older maternal age at delivery (OR 8.93, 95% CI: 1.87-42.62) and maternal unemployment (OR 4.75, 95%CI: 1.40-16.09). Reading aloud emerged as a protective practice, emphasizing its potential in early interventions. Conclusions: These results highlight the need for continuous monitoring of WS and the importance of positive parental practices in mitigating developmental risks. Early identification by primary care practitioners is crucial in addressing developmental concerns early and improving long-term outcomes.

Indexed as

child developmentcohort studyearly interventionneurodevelopmental disordersrisk factorswarning signs

Identifiers

PMID41809716
PMCPMC12969220

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.