Evidence map›Paper›PMID 41810066›Full record

ArticleExploration (Beijing, China)2026

Ganoderic Acids Alleviate Neuroinflammation by Targeting Myeloid Differentiation Factor 2 for Ischemic Stroke Therapy.

Ang Ma, Yinhua Zhu, Yi Ying, Shuyuan Wang, Jingsong Zhang, Na Feng, Yazhu Quan, Guangying Shao, Dandan Liu, Shujie Zhang and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exploration (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Food science & nutrition · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ang MaState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.ORCID https://orcid.org/0009-0002-9988-8670
Yinhua ZhuBeijing Advanced Innovation Center for Food Nutrition and Human Health Department of Nutrition and Health China Agricultural University Beijing China.ORCID https://orcid.org/0009-0002-2803-3579
Yi YingState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Center and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China.
Shuyuan WangState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Jingsong ZhangNational Engineering Research Center of Edible Fungi Institute of Edible Fungi Shanghai Academy of Agricultural Sciences Shanghai China.
Na FengNational Engineering Research Center of Edible Fungi Institute of Edible Fungi Shanghai Academy of Agricultural Sciences Shanghai China.
Yazhu QuanState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Guangying ShaoState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Dandan LiuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Center and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China.
Shujie ZhangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Center and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China.
Xiaoqiang GengState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Hong ZhouState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Min LiState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.
Dongmei LinNational Engineering Research Center of Juncao Technology Fujian Agriculture and Forestry University Fuzhou Fujian China.
Lianfu WangNational Engineering Research Center of Juncao Technology Fujian Agriculture and Forestry University Fuzhou Fujian China.
Guang LiangChemical Biology Research Center School of Pharmaceutical Sciences Wenzhou Medical University Wenzhou Zhejiang China.
Shaowei LiFrederick National Laboratory for Cancer Research National Cancer Institute, National Institutes of Health (NIH) Frederick Maryland USA.
Baoxue YangState Key Laboratory of Vascular Homeostasis and Remodeling Department of Pharmacology School of Basic Medical Sciences Peking University Beijing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation plays a critical role in cerebral ischemic injury, making it an important therapeutic target for stroke treatment. Ganoderic acids (GAs), the primary bioactive compounds isolated from

Indexed as

ganoderic acidischemic strokemicrogliamyeloid differentiation protein 2neuroinflammationToll‐like receptor 4

Identifiers

PMID41810066
PMCPMC12970185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.