ArticleTranslational pediatrics2026
Prevalence and molecular characteristics of respiratory syncytial virus in hospitalized children in Shenzhen during the COVID-19 pandemic: a retrospective study.
Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The prevalence of respiratory syncytial virus (RSV) caused acute lower respiratory tract infections (ALRTI) among children, which have made children susceptible to severe infection. This study aims to determine the prevalence of RSV among hospitalized children in Shenzhen, Guangdong Province, China, during the coronavirus disease 2019 (COVID-19) pandemic and examine any variation in molecular characteristics and clinical presentations. Methods: Eligible children during the study period were retrospectively collected, and nasopharyngeal swabs were collected. RSV-positive samples were grouped into different subtypes using specific primers and into genotypes through sequencing of the second hypervariable region of the G gene. Clinical data, including demographic data, clinical presentations, laboratory and imaging results, were also collected from the medical records of these children. Those cases with COVID-19 antigen tests positive in this study were excluded, along with those involving mixed infections. Results: Two hundred and seventeen (57.11%) of the 380 samples tested positive for RSV. Sequencing was successful in 51 of the samples, of which 27 belonged to RSV-A and 24 to RSV-B. Phylogenetic analysis of the 51 successfully sequenced RSV isolates revealed that all RSV-A strains were ON1 genotype, while all RSV-B strains were BA9. RSV-A ON1 genotype and RSV-B BA9 genotype stratified data showed that RSV-A subtype ON1 infection children were more likely to have longer hospital length of stay (P=0.04) and higher risk of pediatric intensive care unit (PICU) admission (P=0.008). Conclusions: During June 2021 to September 2021 in Shenzhen, Guangdong Province, China, RSV-A ON1 genotype was predominantly prevalent. RSV-A subtype ON1 infected children had longer hospital stays and higher PICU admission risk. Further studies are needed to explore the relationship between molecular biological features and clinical presentation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.