Evidence map›Paper›PMID 41810365›Full record

ArticlemedRxiv : the preprint server for health sciences2026

The Mucosal Cytokine Landscape of Acute Gonorrhea Using a Controlled Human Infection Model.

Michael P Motley, Marcia M Hobbs, Andreea Waltmann, Andrew N Macintyre, Joseph A Duncan

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael P MotleyDivision of Infectious Diseases, Department of Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-4271-1375
Marcia M HobbsInstitute for Global Health and Infectious Diseases, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Andreea WaltmannInstitute for Global Health and Infectious Diseases, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Andrew N MacintyreDepartment of Medicine, School of Medicine, Duke University, Durham, North Carolina, USA.
Joseph A DuncanDivision of Infectious Diseases, Department of Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-4438-2018

Funding

Regional Biocontainment Laboratory (RBL)UC6AI058607 · NIAID · DUKE UNIVERSITY · PI WILLIAMS, R SANDERS · 2003 to 2005
$16.3M
Resources and Workforce Development for the Regional Biocontainment LaboratoriesUC7AI180254 · NIAID · DUKE UNIVERSITY · PI Herman F Staats · 2023 to 2026
$14.0M
Regional Biocontainment Laboratories Facility and Building System Upgrades SupportG20AI167200 · NIAID · DUKE UNIVERSITY · PI STAATS, HERMAN F · 2021 to 2022
$6.6M
CTSA K12 Program at UNCK12TR004416 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michelle Hernandez, Jonathan J Juliano · 2023 to 2026
$6.5M
Experimental human infection with isogenic mutants of Neisseria gonorrhoeaeU01AI114378 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOBBS, MARCIA METZGAR · 2015 to 2019
$2.8M
NCATS NIH HHS K12 TR004416NIAID NIH HHS G20 AI167200NIAID NIH HHS U01 AI114378NIAID NIH HHS UC6 AI058607NIAID NIH HHS UC7 AI180254
6 · The paper itself

Abstract

The host response to

Indexed as

gonorrheahuman challengeimmune responseNeisseria gonorrhoeae

Identifiers

PMID41810365
PMCPMC12970356

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.