Evidence map›Paper›PMID 41810422›Full record

ArticleCurrent research in food science2026

Activity-specificity balanced Au@Pt nanozyme immunoassay via Dual-Au deposition for enhanced mycotoxin detection.

Rentang Huang, Yuxin Huang, Jinrong Yao, Yi Lin, Xiangsheng Zhao, Qian Li, Shumei Wang, Lei Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. CuCurrent research in food science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rentang HuangKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Yuxin HuangKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Jinrong YaoKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Yi LinKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Xiangsheng ZhaoHainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine & Hainan Branch of the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Haikou, 570311, China.
Qian LiCollege of Basic Medical Science, Ningxia Medical University, Yinchuan, 750004, China.
Shumei WangKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Lei ZhangKey Laboratory of Digital Quality Evaluation of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine & Guangdong Provincial Traditional Chinese Medicine Quality Engineering and Technology Research Center, Guangdong Pharmaceutical University, Guangzhou, 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycotoxins persistently threaten global food and herbal medicine safety, demanding the urgent development of detection methods that integrate high sensitivity with strong specificity. Conventional nanozyme-based immunoassays, however, are constrained by the inherent trade-off between sensitivity and specificity, limiting their performance. In this study, we propose a dual-gold enhanced Au@Pt nanozyme-linked immunosorbent assay (Au@Pt/Au-ELISA), which leverages a rationally engineered sequential optimization paradigm to fundamentally overcome the intrinsic trade-off between sensitivity and specificity. The method innovatively integrates mild gold deposition for background suppression with targeted catalytic site amplification, thereby maximizing the catalytic potential of Au@Pt nanozymes while preserving antibody recognition. The dual-stage design significantly enhances nanozyme activity, reducing the usage of antibody probes to 14.3% and 33.3% of that in the original scheme for zearalenone (ZEN) and aflatoxin B

Indexed as

Au@Pt/AuELISAGold enhancementMycotoxinSignal amplification

Identifiers

PMID41810422
PMCPMC12969382

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.