Evidence map›Paper›PMID 41810463›Full record

ArticleAsian journal of pharmaceutical sciences2026

Porous Baicalin-Fe(III) ICP@Propofol nanocomposites for enhanced anesthetic efficacy and reduced toxicity via neuroprotection and ultrasound assistance.

Shuo Zhang, Lei Shi, Jiansheng He, Ji Xia, Shunlian Li, Rong Wang, Qingyan Ma, Mingting Zhu, Peng Tang, Hao Tian and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shuo ZhangDepartment of Psychiatry, Center for Brain Science, Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Lei ShiDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Jiansheng HeDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Ji XiaDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Shunlian LiDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Rong WangThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Qingyan MaDepartment of Psychiatry, Center for Brain Science, Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Mingting ZhuThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Peng TangThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Hao TianDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Feiqian WangDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Mingxi WanThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Daocheng WuThe Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Wei GaoDepartment of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Xiancang MaDepartment of Psychiatry, Center for Brain Science, Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Feng ZhuDepartment of Psychiatry, Center for Brain Science, Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To enhance the anesthetic efficacy of propofol while mitigating its systemic toxicity and irreversible developmental neurotoxicity, we developed a strategy leveraging the neuroprotective effects of baicalin in combination with propofol anesthesia via baicalin-based nanocomposites. High propofol-loaded porous Baicalin-Fe(III) infinite coordination polymer@propofol nanocomposites were synthesized, wherein baicalin coordinates with Fe

Indexed as

BaicalinInfinite coordination polymerNeuroprotectionPropofolUltrasound

Identifiers

PMID41810463
PMCPMC12890820

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.