Evidence map›Paper›PMID 41810527›Full record

Trial reportJournal of psychopharmacology (Oxford, England)2026

The effects of transcranial direct current stimulation (tDCS) on subjective, autonomic and neuropsychological response in the 7.5% CO

Joanna Astrid Miler, Daniel Meron, David S Baldwin, Matthew Garner

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychopharmacology (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna Astrid MilerDepartment of Psychology, School of Social Sciences, Edinburgh Napier University, UK.ORCID 0000-0001-6664-7104
Daniel MeronClinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.
David S BaldwinClinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.
Matthew GarnerSchool of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnxiety is characterized by hypervigilance, distractibility and selective processing of negative information. There is growing evidence that prefrontal function underlies biases in threat processing and attention control in anxiety. We examined the effect of 20 min of 2 mA dorsolateral prefrontal cortex transcranial direct current stimulation (tDCS) (bipolar-balanced montage) on subjective anxiety, autonomic arousal and threat processing in the 7.5% CO

methodsA between-subjects healthy volunteer double-blind randomized design compared 2 mA tDCS stimulation of the PFC versus sham tDCS on subjective anxiety, autonomic arousal and antisaccade performance during 7.5% CO

resultstDCS did not moderate subjective and autonomic response to CO

conclusionTwenty minutes of active 2 mA tDCS over the left dorsolateral prefrontal cortex may reduce threat processing biases during experimentally induced anxiety and could help target early positive changes in emotion processing.

Indexed as

AnxietyAutonomic Nervous SystemCarbon DioxideTranscranial Direct Current StimulationAdultArousalAttentionDorsolateral Prefrontal CortexDouble-Blind MethodFemaleHumansMalePrefrontal CortexYoung AdultCarbon Dioxideanxietycarbon dioxide challengecognitive biasdirect current stimulationnoninvasive brain stimulation

Identifiers

PMID41810527
PMCPMC13490695

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.