Evidence mapPaperPMID 41811219Full record

ArticleACS chemical neuroscience2026

Neuroprotective Effects of Furanoditerpenes from

Noelia Castedo, Amparo Alfonso, Rebeca Alvariño, Dawrin Pech-Puch, Lucía Ageitos, Jaime Rodríguez, Mercedes R Vieytes, Carlos Jiménez, Luis M Botana

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noelia CastedoDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.
Amparo AlfonsoDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0003-1572-9016
Rebeca AlvariñoDepartamento de Fisiología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0001-8796-1389
Dawrin Pech-PuchCentro Interdisciplinar de Química e Bioloxía (CICA) e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 15071 A Coruña, España.
Lucía AgeitosCentro Interdisciplinar de Química e Bioloxía (CICA) e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 15071 A Coruña, España.
Jaime RodríguezCentro Interdisciplinar de Química e Bioloxía (CICA) e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 15071 A Coruña, España.ORCID 0000-0001-5348-6970
Mercedes R VieytesDepartamento de Fisiología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.
Carlos JiménezCentro Interdisciplinar de Química e Bioloxía (CICA) e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, 15071 A Coruña, España.ORCID 0000-0003-2628-303X
Luis M BotanaDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0003-2153-6608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemia induces oxidative stress and mitochondrial dysfunction in microglia, contributing to neuro-inflammation and neuronal damage. Five furanoditerpenes

Indexed as

DiterpenesMicrogliaNeuroprotective AgentsPeptidyl-Prolyl Isomerase FPoriferaReperfusion InjuryAnimalsCell LineCell SurvivalFuransMembrane Potential, MitochondrialMiceOxidative StressReactive Oxygen SpeciesDiterpenesFuransNeuroprotective AgentsPeptidyl-Prolyl Isomerase FPPIF protein, mouseReactive Oxygen Speciescyclophilin Dfuranoditerpenesinflammationischemiamicroglia

Identifiers

PMID41811219
PMCPMC13047538

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.