Evidence map›Paper›PMID 41811515›Full record

ReviewMolecular genetics and genomics : MGG2026

Small but big player: the important role of microRNAs in legume crops.

Flavia Thiebaut, Maria Clara Urquiaga, Paula Machado de Araújo, Aislan de Carvalho Vivarini, Clicia Grativol

Abstract readReview
In one paragraph

Review in Molecular genetics and genomics : MGG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Flavia ThiebautLaboratório de Bioquímica e Biologia Molecular de Plantas e Microrganismos, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Bloco M - Rua Prof. Marcos Waldemar de Freitas Reis - São Domingos, , Niterói, RJ, 24210-201, Brazil.
Maria Clara UrquiagaLaboratório de Biologia Molecular de Plantas, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Cidade Universitária, Avenida Carlos Chagas Filho, 373, CCS, Bl.L-29ss, Rio de Janeiro, RJ, 21941-599, Brazil.
Paula Machado de AraújoLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego, 2000, P5 - sala 228, Parque Califórnia, Campos dos Goytacazes, RJ, 28013- 602, Brazil.
Aislan de Carvalho VivariniLaboratório de Biologia Molecular Mitocondrial, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Bloco M - Rua Prof. Marcos Waldemar de Freitas Reis - São Domingos, Niterói, RJ, 24210-201, Brazil.
Clicia GrativolLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego, 2000, P5 - sala 228, Parque Califórnia, Campos dos Goytacazes, RJ, 28013- 602, Brazil. cgrativol@uenf.br.ORCID http://orcid.org/0000-0002-8873-701X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Legumes are essential components of global cropping systems due to their nutritional value and contribution to sustainable agriculture. Among the regulatory molecules, small RNAs (sRNAs), particularly microRNAs (miRNAs), play crucial roles in plant development and in responses to biotic and abiotic stresses. miRNAs regulate genes involved in diverse developmental processes, including nodule formation, which is fundamental for the nitrogen-fixing symbiosis that characterizes legumes. Functional studies have demonstrated that miRNAs are key modulators of plant defense, contributing to resistance against pathogens and environmental challenges. Moreover, miRNAs also participate in cross-kingdom communication, such as plant-bacteria interactions, influencing symbiotic efficiency. Advances in molecular biology have enabled the manipulation of miRNAs and their targets for crop improvement. Current approaches include the design of artificial miRNAs (amiRNA), modulation of miRNA expression through miRNA-encoded peptides, genome editing of non-coding genes using CRISPR/Cas9, and the application of RNA interference (RNAi) technology. Together, these strategies highlight the potential of miRNA-based tools in plant biotechnology. A deeper understanding of the molecular mechanisms governing miRNA-mediated gene silencing will provide powerful resources for optimizing legume productivity and resilience within sustainable agricultural systems.

Indexed as

Crops, AgriculturalFabaceaeMicroRNAsRNA, PlantGene Expression Regulation, PlantPlant DevelopmentRNA InterferenceSymbiosisMicroRNAsRNA, PlantBiotechnological applicationEnvironmental responseGene regulationPlant developmentSmall RNA

Identifiers

PMID41811515
PMCPMC12979330

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.