Evidence map›Paper›PMID 41811612›Full record

ReviewHeart failure reviews2026

Heart failure evidence update 2026.

Sotiria Liori, Chris J Kapelios, Gianluigi Savarese, Gerasimos Filippatos

Abstract readReview
In one paragraph

Review in Heart failure reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sotiria LioriHeart Failure Unit, Department of Cardiology, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Haidari, Athens, 12462, Greece.
Chris J KapeliosHeart Failure Unit, Department of Cardiology, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Haidari, Athens, 12462, Greece.
Gianluigi SavareseDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.
Gerasimos FilippatosHeart Failure Unit, Department of Cardiology, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Haidari, Athens, 12462, Greece. gfilippatos@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interval since the 2021 European Society of Cardiology (ESC) Guidelines and 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America (AHA/ACC/HFSA) Guidelines publications has witnessed an unprecedented volume of evidence that substantially expands the therapeutic landscape across the entire ejection fraction (EF) spectrum. Major developments include the emergence of non-steroidal mineralocorticoid receptor antagonists and incretin-based therapies for heart failure (HF) with mildly reduced and preserved EF, the validation of rapid guideline-directed medical therapy optimization strategies in acute HF, and new evidence supporting digitalis glycosides in HF patients with reduced EF. Device-based care has evolved with transcatheter edge-to-edge repair for valvular heart disease. These data are likely to reshape contemporary clinical practice.

Indexed as

Heart FailurePractice Guidelines as TopicStroke VolumeDigitalis GlycosidesHumansMineralocorticoid Receptor AntagonistsDigitalis GlycosidesMineralocorticoid Receptor AntagonistsClinical trialsHeart failureMedical devicesOutcomesPharmacotherapy

Identifiers

PMID41811612
PMCPMC12979370

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.