Evidence map›Paper›PMID 41811730›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2026

Plasma linoleic acid is related to lower hepatic steatosis index and higher linoleate-rich cardiolipin in adults with MAFLD.

Ali Kalhori, Rachel M Cole, Stephan Zarich, Na Li, Arunark Kolipaka, Ai Ni, Genevieve C Sparagna, Martha A Belury

Abstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali KalhoriDepartment of Food Science and Technology, The Ohio State University, Columbus, Ohio, United States.
Rachel M ColeDepartment of Food Science and Technology, The Ohio State University, Columbus, Ohio, United States.
Stephan ZarichDepartment of Food Science and Technology, The Ohio State University, Columbus, Ohio, United States.
Na LiDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, United States.
Arunark KolipakaDepartment of Radiology, The Ohio State University, Columbus, Ohio, United States.
Ai NiDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, United States.
Genevieve C SparagnaDivision of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-9543-4626
Martha A BeluryDepartment of Food Science and Technology, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0002-6480-4281

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUM1TR004548 · NCATS · OHIO STATE UNIVERSITY · PI CYNTHIA A GERHARDT, JULIE A. JOHNSON · 2023 to 2026
$22.0M
Improving sarcopenia by targeting mitochondriaR01AG080184 · NIA · OHIO STATE UNIVERSITY · PI MARTHA A BELURY, Brian C Clark · 2023 to 2026
$2.6M
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UM1TR004548NCATS NIH HHS UM1 TR004548NIA NIH HHS R01 AG080184OSU | Ohio Agricultural Research and Development Center, Ohio State University (OARDC)United Soybean Board (USB) 2411-108-0101
6 · The paper itself

Abstract

Linoleic acid (LA, C18:2n-6) is a required nutrient that supports mitochondrial function as a component of the inner mitochondrial membrane, cardiolipin (CL). Tetralinoleoyl CL (LA

Indexed as

CardiolipinsFatty LiverLinoleic AcidLiverAdultAgedFemaleHumansInsulin ResistanceLeukocytes, MononuclearMaleMiddle AgedCardiolipinsLinoleic Acidhepatic steatosislinoleic acidMAFLDtetralinoleoyl-cardiolipintype 2 diabetes

Identifiers

PMID41811730
PMCPMC13255092

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.