Evidence map›Paper›PMID 41811943›Full record

ArticleScience advances2026

A previously unrecognized class of fungal ice-nucleating proteins with bacterial ancestry.

Rosemary J Eufemio, Mariah Rojas, Kaden Shaw, Ingrid de Almeida Ribeiro, Hao-Bo Guo, Galit Renzer, Kassaye Belay, Haijie Liu, Parkesh Suseendran, Xiaofeng Wang and 7 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rosemary J EufemioDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.ORCID 0000-0003-2981-7316
Mariah RojasSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0001-5535-7742
Kaden ShawDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.ORCID 0000-0001-8810-3503
Ingrid de Almeida RibeiroDepartment of Chemistry, The University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-8418-3806
Hao-Bo GuoMaterials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH 45433, USA.ORCID 0000-0003-1321-1758
Galit RenzerDepartment of Molecular Spectroscopy, Max Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0009-0004-7712-2310
Kassaye BelaySchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0001-6402-7200
Haijie LiuSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Parkesh SuseendranSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Xiaofeng WangSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0002-3850-3274
Janine Fröhlich-NowoiskyDepartment of Multiphase Chemistry, Max Planck Institute for Chemistry, Mainz 55128, Germany.ORCID 0000-0002-1278-0054
Ulrich PöschlDepartment of Multiphase Chemistry, Max Planck Institute for Chemistry, Mainz 55128, Germany.
Mischa BonnDepartment of Molecular Spectroscopy, Max Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0001-6851-8453
Rajiv J BerryMaterials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH 45433, USA.ORCID 0000-0001-6355-8667
Valeria MolineroDepartment of Chemistry, The University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-8577-4675
Boris A VinatzerSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0003-4612-225X
Konrad MeisterDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.ORCID 0000-0002-6853-6325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ice-nucleating proteins (INpros) catalyze ice formation at high subzero temperatures, with major biological and environmental implications. While bacterial INpros have been structurally characterized, their counterparts in other organisms have remained largely unknown. Here, we identify membrane-independent proteins in fungi of the

Indexed as

Bacterial Outer Membrane ProteinsBacterial ProteinsFungal ProteinsIceEscherichia coliModels, MolecularPhylogenySaccharomyces cerevisiaeBacterial Outer Membrane ProteinsBacterial ProteinsFungal ProteinsIceice nucleation protein

Identifiers

PMID41811943
PMCPMC12978214

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.