Evidence map›Paper›PMID 41812879›Full record

ArticleThe Journal of biological chemistry2026

OGG1 increases exercise endurance via elevated skeletal muscle FGF21.

Bhavya Blaze, Priyanka Sharma, Bhavya Prakash Gupta, Souvik Mandal, Sai Santosh Babu Komakula, Tracy Anthony, Emmanuel Marfo, Harini Sampath

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bhavya BlazeDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Priyanka SharmaDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Bhavya Prakash GuptaRutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Souvik MandalDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Sai Santosh Babu KomakulaRutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Tracy AnthonyDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA.
Emmanuel MarfoRutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA.
Harini SampathDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA. Electronic address: harini.sampath@rutgers.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The base excision repair pathway maintains genomic integrity in the face of oxidative insult. It is initiated by DNA glycosylases such as 8-oxoguanine DNA glycosylase (OGG1) and is implicated in various pathologies, such as cancers and neurodegenerative diseases. Base excision repair proteins also modulate body weight and metabolic health. Mice lacking OGG1 are susceptible to obesity and its sequelae, whereas overexpression of human OGG1 (in OGG1-transgenic mice; Ogg1

Indexed as

DNA GlycosylasesFibroblast Growth FactorsMuscle, SkeletalPhysical Conditioning, AnimalPhysical EnduranceAnimalsHumansMaleMiceMice, TransgenicDNA Glycosylasesfibroblast growth factor 21Fibroblast Growth FactorsOgg1 protein, mousebase excision repairexercise tolerancefibroblast growth factormitochondriamyokineskeletal muscle

Identifiers

PMID41812879
PMCPMC13068818

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.