Evidence map›Paper›PMID 41813898›Full record

ArticleNature2026

A mechanism to initiate emergency type 2 myelopoiesis.

Alexandre Fagnan, Cristina Di Genua, Yiran Meng, Roy Drissen, Zishan Zhang, Bowen Zhang, Padraic G Fallon, Vassilis Pachnis, Erika J Mancini, Fränze Progatzky and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexandre FagnanMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Cristina Di GenuaMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Yiran MengMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.ORCID http://orcid.org/0000-0002-9333-2383
Roy DrissenMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.ORCID http://orcid.org/0000-0002-8574-5014
Zishan ZhangMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Bowen ZhangMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Padraic G FallonSchool of Medicine, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0002-8401-7293
Vassilis PachnisNervous System Development and Homeostasis Laboratory, Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0001-9733-7686
Erika J ManciniSchool of Life Sciences and Sussex Drug Discovery Centre, University of Sussex, Brighton, UK.
Fränze ProgatzkyNervous System Development and Homeostasis Laboratory, Francis Crick Institute, London, UK.
Claus NerlovMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. claus.nerlov@imm.ox.ac.uk.ORCID http://orcid.org/0000-0002-0544-735X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune responses to parasite infection involve the increased production of basophils and eosinophils. These two myeloid cell types have key roles in type 2 anti-parasite immunity

Indexed as

BasophilsEosinophilsMyelopoiesisStrongylida InfectionsAdaptor Proteins, Signal TransducingAnimalsCell DifferentiationCell LineageChromatinErythropoiesisFemaleGATA2 Transcription FactorInterleukin-33LIM Domain ProteinsMaleMast CellsAdaptor Proteins, Signal TransducingChromatinGata2 protein, mouseGATA2 Transcription FactorIl33 protein, mouseInterleukin-33LIM Domain ProteinsNuclear ProteinsTranscription Factors

Identifiers

PMID41813898
PMCPMC13148993

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.