Evidence map›Paper›PMID 41815754›Full record

ReviewObesity pillars2026

Obesity and female reproductive health in Asian population.

Krasean Panyakhamlerd, Areepan Sophonsritsuk, Tawiwan Pantasri, Ammarin Suwan, Nuttanun Panyawongudom, Parinya Samakkarnthai

Abstract readReview
In one paragraph

Review in Obesity pillars, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krasean PanyakhamlerdDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Areepan SophonsritsukDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Tawiwan PantasriDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Ammarin SuwanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nuttanun PanyawongudomDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Parinya SamakkarnthaiDivision of Endocrinology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is a rising global health issue, especially among women, with important effects on reproductive health. This problem is becoming more urgent in Asia, reflecting worldwide trends in increasing rates. Despite expanding evidence, integrated guidance remains limited. This narrative clinical review synthesizes current evidence to provide practical clinical recommendations. Methods: This was a narrative clinical review informed by expert opinion and developed by the Thai Interest Group in Obesity and Female Reproductive Health through an interdisciplinary collaborative process. The approach included a comprehensive literature review across various databases to gather high-quality scientific evidence, clinical guidelines, and epidemiological data on the connection between obesity and female reproductive health. Results: The review summarizes current evidence on how obesity affects key reproductive conditions, including polycystic ovary syndrome (PCOS), infertility, and menopause. Obesity is strongly associated with PCOS, contributing to hormonal imbalances, insulin resistance, and metabolic dysfunction. It also impacts fertility by disrupting ovarian function and increasing the risk of pregnancy complications. Furthermore, menopausal women with obesity face higher risks of cardiovascular disease, metabolic disorders, and severe menopausal symptoms due to increased visceral adiposity and hormonal changes. Evidence supports the role of weight management, including lifestyle changes and pharmacological interventions, in improving reproductive outcomes. Weight reduction has been shown to improve ovulation, menstrual regularity, and fertility in women with PCOS and obesity. Anti-obesity drugs have proven effective for weight loss and enhancing reproductive health. Conclusion: Obesity has significant negative effects on female reproductive health from adolescence to menopause but these issues can be reversed with effective weight management. With the increasing rate of obesity in Asia, healthcare professionals must prioritize weight management strategies to mitigate its harmful impact on women's reproductive health.

Indexed as

Anti-obesity medicationsFemale reproductive healthInfertilityMenopauseObesityPCOS

Identifiers

PMID41815754
PMCPMC12972537

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.