Evidence mapPaperPMID 41815906Full record

ArticleRSC advances2026

Pyrazole/pyrimidine derivatives endowed with azobenzenes as dual EGFR

Kurls E Anwer, Mohamed A Abdelgawad, Felemban Athary Abdulhaleem M, Nour E A Abd El-Sattar, Ahmed El-Morsy, Tamer Nasr, Mohammed Elmowafy, Khaled El-Adl, Naglaa M Ahmed

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kurls E AnwerDepartment of Chemistry, Faculty of Science, Ain Shams University Abbassia Cairo Egypt.ORCID https://orcid.org/0000-0003-3017-8806
Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University Sakaka 72388 Saudi Arabia mhmdgwd@ju.edu.sa.
Felemban Athary Abdulhaleem MDepartment of Biology, College of Sciences, Umm Al-Qura University Makkah 21955 Saudi Arabia.
Nour E A Abd El-SattarDepartment of Chemistry, Faculty of Science, Ain Shams University Abbassia Cairo Egypt.ORCID https://orcid.org/0000-0001-6680-4448
Ahmed El-MorsyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Boys), Al-Azhar University Nasr City Cairo 11884 Egypt.
Tamer NasrDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Capital University (Formerly Helwan University) Ain-Helwan Cairo 11795 Egypt.ORCID https://orcid.org/0000-0003-0104-9765
Mohammed ElmowafyDepartment of Pharmaceutics, College of Pharmacy, Jouf University Sakaka 72388 Saudi Arabia.
Khaled El-AdlPharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development Cairo Egypt khaled.eladl@hu.edu.eg eladlkhaled74@yahoo.com.ORCID https://orcid.org/0000-0002-8922-9770
Naglaa M AhmedPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Capital University (Formerly Helwan University) Ain-Helwan Cairo 11795 Egypt.ORCID https://orcid.org/0000-0001-5864-2370

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New pyrazole/pyrimidine derivatives endowed with azobenzenes were synthesized using microwave and traditional methods. Our compounds were assessed for cytotoxicity against HepG2, MCF-7, HCT-116 and A549 cell lines as dual inhibitors of EGFR

Identifiers

PMID41815906
PMCPMC12973379

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.