Evidence map›Paper›PMID 41816098›Full record

ArticleClinical & translational immunology2026

Influenza virus infection drives upregulation of CD84 across a broad range of immune cells.

Xiaoxiao Jia, Isabelle Jh Foo, Hayley A McQuilten, Jeremy Chase Crawford, Aira F Cabug, Deborah Gebregzabher, Janet Chou, Robert C Mettelman, Tanya Novak, Lee-Ann Van de Velde and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical & translational immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xiaoxiao Jia *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Isabelle Jh Foo *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Hayley A McQuilten *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Jeremy Chase CrawfordDepartment of Host-Microbe Interactions St. Jude Children's Research Hospital Memphis TN USA.
Aira F CabugDepartment of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Deborah GebregzabherDepartment of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Janet ChouDivision of Immunology Boston Children's Hospital, Harvard Medical School Boston MA USA.
Robert C MettelmanDepartment of Host-Microbe Interactions St. Jude Children's Research Hospital Memphis TN USA.
Tanya NovakDepartment of Anesthesiology, Critical Care, and Pain Medicine Boston Children's Hospital Boston MA USA.
Lee-Ann Van de VeldeDepartment of Host-Microbe Interactions St. Jude Children's Research Hospital Memphis TN USA.
Ryan S ThwaitesNational Heart and Lung Institute Imperial College London London UK.
Adrienne G RandolphDepartment of Anesthesiology, Critical Care, and Pain Medicine Boston Children's Hospital Boston MA USA.
Paul G ThomasDepartment of Host-Microbe Interactions St. Jude Children's Research Hospital Memphis TN USA.
Jianqing XuShanghai Public Health Clinical Centre and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education/Health, Shanghai Medical College Fudan University Shanghai China.
Zhongfang WangDepartment of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.ORCID https://orcid.org/0000-0003-3236-5170
Katherine Kedzierska *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Lukasz Kedzierski *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.
Brendon Y Chua *Department of Microbiology and Immunology Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Our previous study in hospitalised patients infected with avian A(H7N9) influenza virus identified Methods: Expression dynamics of Results: Elevated Conclusion: Our findings revealed the link between high CD84 expression in humans and recovery from respiratory viral infections. In mice, CD84 expression increased across a broad range of immune cell populations, with CD84 expression on activated T-cell populations correlating with less severe disease.

Indexed as

CD84infectioninfluenzaOLAHT cells

Identifiers

PMID41816098
PMCPMC12971607

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.