ArticleiScience2026
Gut-derived bacterial membrane vesicles in prediabetes: Vesicle composition dictates inflammatory properties.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Systemic inflammation relates to the pathophysiology of metabolic diseases such as obesity or type 2 diabetes. Understanding aberrant microbiota-host interactions is essential for comprehending their pathogenesis. Gut bacteria produce bacterial membrane vesicles (bMVs) reflecting bacterial metabolism and activity. Importantly, in animal models, these vesicles can reach organs and affect metabolism by inducing inflammation. We investigated feces-derived gut bacteria and bMVs in participants diagnosed with prediabetes and in healthy controls. Vesicle and bacterial DNA repertoires were found to be vastly different, with Gram-negative bacterial taxa dominating at the vesicle level (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.