Evidence map›Paper›PMID 41817624›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2026

The costs and benefits of striving: Subclinical cardiovascular disease, depression, and hostility as children navigate adversity.

Brooks B Gump, Stefanie Pilkay, Xiafei Wang, Sara Vasilenko, Nader H Atallah-Yunes, Sarah Woolf-King, Stephen Maisto, Edith Chen, Craig K Ewart

Abstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Brooks B GumpDepartment of Public Health, Syracuse University.ORCID 0000-0001-5906-6651
Stefanie PilkaySchool of Social Work, Syracuse University.
Xiafei WangCollege of Social Work, University of Kentucky.
Sara VasilenkoDepartment of Human Development and Family Science, Syracuse University.
Nader H Atallah-YunesDepartment of Pediatric Cardiology, University of Rochester School of Medicine, University of Rochester.
Sarah Woolf-KingDepartment of Psychology, Syracuse University.ORCID 0000-0002-5612-1114
Stephen MaistoDepartment of Psychology, Syracuse University.ORCID 0000-0001-5470-102X
Edith ChenDepartment of Psychology, Northwestern University.
Craig K EwartDepartment of Psychology, Syracuse University.

Funding

Environmental Toxicants, Race, and Cardiovascular Disease Risk in ChildrenR01ES023252 · NIEHS · SYRACUSE UNIVERSITY · PI GUMP, BROOKS B. · 2013 to 2016
$1.9M
NIEHS NIH HHS R01 ES023252NIH HHS
6 · The paper itself

Abstract

backgroundAdversity (e.g., poverty, discrimination, or stress) does not always produce harmful effects. "Striving" against adversity has been linked to positive psychological outcomes, such as lower depression, suggesting resilience; however, striving against severe adversity appears to simultaneously produce cardiovascular disease (CVD) risk (framed in the literature as "John Henryism").

methodWe assessed striving (self-report survey) and adversity (nine indices, including socioeconomic status, discrimination, and city stress) in a sample of 9-11-year-old children (

resultsAfter adjusting for covariates, we found a number of significant Striving × Adversity interactions (

conclusionsThis pattern we observed is becoming consistent in the literature, whereby striving against adversity produces psychological and physical benefits when adversity is below a certain threshold but produces continued psychological benefits yet CVD risks when adversity rises beyond this threshold. Efforts to protect children living in severe adversity might benefit from interventions designed to maintain the psychological benefits associated with striving against adversity while simultaneously blocking any harm to the cardiovascular system. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Adverse Childhood ExperiencesCardiovascular DiseasesDepressionHostilityStress, PsychologicalBlood PressureChildFemaleHumansMale

Identifiers

PMID41817624
PMCPMC13003311

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.