ArticleLangenbeck's archives of surgery2026
Changes in psoas muscle area in patients with colorectal cancer three years after surgery: a longitudinal approach.
Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate long-term changes in psoas muscle area after colorectal cancer (CRC) surgery and their association with preoperative clinical characteristics and mortality. Skeletal muscle loss predicts poor CRC outcomes, but evidence on postoperative changes is limited.
methodsWe included 272 patients with localized CRC who underwent elective surgery at Herlev Hospital, Denmark, between 2014 and 2019. Computed tomography (CT) scans before surgery and at three-year follow-up were used to assess psoas muscle area at the L3 vertebral level. Change in muscle area was categorized as > 5% decrease, no change, or > 5% increase. Associations between preoperative clinical characteristics and mortality were analyzed in relation to muscle change.
resultsAt three-year follow-up after surgery, 39% of patients showed a > 5% decrease in psoas muscle area, 33% had no change, and 28% had a > 5% increase. The results demonstrated that both Union for International Cancer Control (UICC) tumor stage and receipt of adjuvant chemotherapy were independently associated with postoperative changes in psoas muscle area. Among patients who did not receive adjuvant chemotherapy, age was associated with muscle area change, whereas no preoperative clinical characteristics were associated with muscle area change among those receiving adjuvant chemotherapy. Importantly, postoperative longitudinal changes in psoas muscle area were not associated with overall mortality.
conclusionA considerable proportion of patients with CRC experience long-term loss of psoas muscle area following surgery. These results underscore the variability in postoperative muscle changes and highlight the need for further research to identify high-risk subgroups.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.