Evidence map›Paper›PMID 41817955›Full record

ReviewInfectious diseases and therapy2026

Navigating the Viral Hepatitis Drug Landscape: New Discoveries and Enduring Challenges. A Narrative Review.

He-Ming Sun, Xing-Yu Wang, Hong-Qin Xu, Yan-Hang Gao

Abstract readReview
In one paragraph

Review in Infectious diseases and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

He-Ming SunDepartment of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Jilin University, Changchun, 130021, Jilin, China.
Xing-Yu WangDepartment of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Jilin University, Changchun, 130021, Jilin, China.
Hong-Qin XuDepartment of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Jilin University, Changchun, 130021, Jilin, China.
Yan-Hang GaoDepartment of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Jilin University, Changchun, 130021, Jilin, China. yanhang@mail.jlu.edu.cn.ORCID http://orcid.org/0000-0001-8590-6706

Funding

National Natural Science Foundation of China 82170602National Natural Science Foundation of China No. U24A20654
6 · The paper itself

Abstract

Viral hepatitis remains a significant challenge for global public health and a leading cause of liver-related morbidity and mortality worldwide, with most cases caused by five hepatotropic viruses: hepatitis A, B, C, D, and E. The World Health Organization has established a goal to eliminate viral hepatitis as a public health threat by 2030. In recent years, advancements in our understanding of its pathogenesis have significantly propelled the development of antiviral drugs, particularly for hepatitis C, for which we now have highly effective therapies with cure rates exceeding 95%. However, achieving complete cures for hepatitis B and D continues to pose challenges, and effective treatments for hepatitis A and E are still lacking. A comprehensive understanding of the latest treatment advancements is crucial for guiding future drug development. This article reviews the most recent advancements in pharmacological interventions for viral hepatitis, summarizes current treatment methods, and provides an outlook on future research and therapeutic strategies, with the aim of improving patient outcomes and alleviating the global burden of liver diseases.

Indexed as

Hepatitis A virusHepatitis B virusHepatitis C virusHepatitis D virusHepatitis E virusTreatmentViral hepatitis

Identifiers

PMID41817955
PMCPMC13043857

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.