Evidence map›Paper›PMID 41821256›Full record

ArticleBrain and behavior2026

Central Abnormalities in Idiopathic Tinnitus With Mild Hearing Loss: Selective Attention and Preprocessing Dysfunction.

Xingqian Shen, Hui Pan, Yingzhao Liu, Ziying Xu, Xiaoye Chen, Qin Liu, Kaijun Xia, Wen Xie, Linlin Wang, Bo Liu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xingqian ShenDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hui PanDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yingzhao LiuDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ziying XuDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaoye ChenDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qin LiuDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kaijun XiaDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wen XieDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Linlin WangDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bo LiuDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hongjun XiaoDepartment of Otorhinolaryngology-Head Neck Surgery and ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

National Key Research and Development Program of China 2023YFC2508000National Key Research and Development Program of China 2023YFC2508001National Key Research and Development Program of China 2023YFC2508400National Natural Science Foundation of China 81670930National Natural Science Foundation of China 82101231Natural Science Foundation of Hubei Province 2021CFB547
6 · The paper itself

Abstract

objectivesTo verify the abnormal brain electrical activity of idiopathic tinnitus through auditory event-related potentials and elucidate the impact of mild hearing loss.

designAuditory event-related potentials were collected from 74 patients with idiopathic tinnitus as the primary complaint (divided into a normal hearing group of 39 and a mild hearing loss group of 35 based on hearing level) and 37 healthy volunteers. Various auditory event-related potential indicators were compared among the groups, and the correlation between these indicators and the clinical characteristics of idiopathic tinnitus patients was analyzed.

resultsIdiopathic tinnitus patients with normal hearing have increased P1 amplitude, delayed P300 latency, decreased P300 amplitude, and decreased mismatch negativity (MMN) amplitude. Idiopathic tinnitus patients with mild hearing loss have further reduced P300 amplitude and delayed MMN latency. In addition, the P300 latency of idiopathic tinnitus patients is significantly correlated with the duration of tinnitus and Tinnitus Handicap Inventory (THI) score, the P300 amplitude is significantly correlated with the Pittsburgh Sleep Quality Index (PSQI) score, and the MMN latency is significantly correlated with the duration of tinnitus.

conclusionPatients with idiopathic tinnitus exhibit abnormalities in multiple auditory event-related potentials, with mild hearing loss exacerbating some of these abnormalities. Idiopathic tinnitus and mild hearing loss may lead to selective attention and preprocessing dysfunction.

Indexed as

AttentionEvoked Potentials, AuditoryHearing LossTinnitusAcoustic StimulationAdultElectroencephalographyEvent-Related Potentials, P300FemaleHumansMaleMiddle Agedauditory event‐related potentialsidiopathic tinnitusmild hearing lossmismatch negativityP300

Identifiers

PMID41821256
PMCPMC13093310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.