Evidence map›Paper›PMID 41821524›Full record

ArticleNeurophotonics2026

Phantom for standardization in functional near-infrared spectroscopy, part 2: optical properties and Monte Carlo simulations.

Caterina Amendola, Antonio Pifferi, Alessandro Torricelli, Dirk Grosenick, Heidrun Wabnitz, David R Busch, Michele Lacerenza, Marianne Floor-Westerdijk, Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno and 2 more

Abstract read
In one paragraph

Article in Neurophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Caterina AmendolaPolitecnico di Milano, Department of Physics, Milan, Italy.ORCID https://orcid.org/0000-0002-6738-9589
Antonio PifferiPolitecnico di Milano, Department of Physics, Milan, Italy.ORCID https://orcid.org/0000-0002-2261-2089
Alessandro TorricelliPolitecnico di Milano, Department of Physics, Milan, Italy.ORCID https://orcid.org/0000-0002-6878-8936
Dirk GrosenickPhysikalisch-Technische Bundesanstalt (PTB), Berlin, Germany.ORCID https://orcid.org/0009-0005-4354-7254
Heidrun WabnitzPhysikalisch-Technische Bundesanstalt (PTB), Berlin, Germany.ORCID https://orcid.org/0000-0002-3846-8659
David R BuschUniversity of Texas Southwestern Medical Center, O'Donnell Brain Institute, Department of Anesthesiology, Neurology, and Biomedical Engineering, Dallas, Texas, United States.ORCID https://orcid.org/0000-0002-9488-944X
Michele LacerenzaPIONIRS s.r.l., Milan, Italy.
Marianne Floor-WesterdijkArtinis Medical Systems, Elst, The Netherlands.
Sanathana Konugolu Venkata SekarBioPixS Limited, Cork, Ireland.ORCID https://orcid.org/0000-0003-0912-1282
Claudia Nunzia GuadagnoBioPixS Limited, Cork, Ireland.ORCID https://orcid.org/0000-0001-9005-7569
Yukari TanikawaNational Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Hiroshi KawaguchiNational Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.ORCID https://orcid.org/0000-0002-1496-2812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: The international standard IEC 80601-2-71 defines requirements for the basic safety and essential performance of medical continuous wave functional near-infrared spectroscopy (fNIRS) equipment, including a set of tests based on a dedicated tissue-equivalent phantom consisting of switchable apertures sandwiched between two diffusing media. Aim: In a companion paper, we described a first implementation of this phantom developed by AIST, its basic characterization of attenuation properties, and results of its application in the testing of commercial fNIRS devices. In the present paper, we provide the absorption and reduced scattering spectra of the AIST phantom and of alternative silicone phantom matrices, complemented with extensive simulations on the effect of the phantom optical properties and geometry on the features of the phantom relevant for the fNIRS standard test. Approach: All spectral measurements were performed with time-domain diffuse optical spectrometers for accurate quantification of the absorption and reduced scattering coefficient, whereas simulations were obtained using a Monte Carlo code. Results: The POM-C matrix of the AIST phantom exhibits negligible absorption ( Conclusions: We provide valid support for researchers and manufacturers to understand the operation of the phantom described in the fNIRS standard and to replicate it in their labs. In addition, we provide a basis for further evolution of the standard itself to encompass alternative probe geometries or functional tests.

Indexed as

absorptionfunctional near-infrared spectroscopyinternational standardphantomscattering

Identifiers

PMID41821524
PMCPMC12978593

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.