Evidence map›Paper›PMID 41822033›Full record

ArticleJournal of clinical medicine research2026

The Role of Epicardial Adipose Tissue in the Development of Atrial Fibrillation: A Systematic Review and Meta-Analysis.

Aida I Tarzimanova, Anna E Bragina, Liubov A Ponomareva, Liubov V Vasileva, Daria D Vanina, Ilya I Shvedov, Anna E Pokrovskaya, Tatiana A Safronova, Tatiana S Vargina, Irakli Zh Loriya and 4 more

Abstract read
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In one paragraph

Article in Journal of clinical medicine research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Aida I TarzimanovaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0001-9536-8307
Anna E BraginaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-2699-1610
Liubov A PonomarevaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-3179-470X
Liubov V VasilevaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0001-5730-7837
Daria D VaninaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0003-1959-370X
Ilya I ShvedovSynergy University, Moscow, Russia.ORCID https://orcid.org/0000-0001-9722-6097
Anna E PokrovskayaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-8875-9032
Tatiana A SafronovaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-2647-5640
Tatiana S VarginaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0003-3076-4231
Irakli Zh LoriyaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0001-8908-7381
Elena N PopovaTareev Clinic of Internal Diseases, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0001-5164-4621
Paria ShooriberisDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0009-0000-3057-0440
Yaroslav M MalininDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0009-0003-1824-5014
Valery I PodzolkovDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-0758-5609

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is the most frequent arrhythmia worldwide that significantly elevates stroke and heart failure risks. Recent developments in imaging research have shown the need for exploring epicardial adipose tissue (EAT) as a contributor to atrial pathology. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in PROSPERO (CRD42022360443), a systematic search was conducted across PubMed, Scopus and Google Scholar using terms related to AF and EAT quantified using computed tomography. Inclusion criteria encompassed Results: Ten studies (851 patients) analyzed showed the relationship between total EAT and AF. Meta-analysis of aggregate data revealed a statistically significant standardized mean difference (SMD) of 0.70 (95% confidence interval (CI), 0.24-1.15; I Conclusions: This meta-analysis demonstrates that total and periatrial EAT correlate with AF; however, periatrial EAT has a more convincing association with AF than total EAT.

Indexed as

Atrial fibrillationPeriatrial epicardial adipose tissueTotal epicardial adipose tissue

Identifiers

PMID41822033
PMCPMC12978394

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.