Evidence mapPaperPMID 41822254Full record

ReviewCureus2026

Chronic Obstructive Pulmonary Disease and Overtraining Syndrome: A Narrative Review.

Bruno Bordoni, Enricomaria Mattia, Bruno Morabito

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bruno BordoniDepartment of Physical Medicine and Rehabilitation, Fondazione Don Carlo Gnocchi, Milan, ITA.
Enricomaria MattiaDepartment of Physical Medicine and Rehabilitation, Centro di Radiologia Medica e Terapia Fisica Morrone, Servizio Sanitario Nazionale, Caserta, ITA.
Bruno MorabitoFaculty of Medicine, Università Cattolica del Sacro Cuore, Agostino Gemelli University Hospital, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is a condition that inevitably leads to airflow limitation. COPD is among the leading causes of increased mortality and morbidity worldwide. A non-invasive and non-pharmacological approach is rehabilitation training, where the patient follows an active program to stimulate the limb and respiratory muscles. Training involves a constant increase in workloads throughout the rehabilitation process. A fundamental concept absent from the literature is that of including training sessions with reduced loads and periods of "unloading" intensity within the rehabilitation program. Without adequate recovery and rest between sessions, the patient may lack the resources necessary to tackle a subsequent demanding rehabilitation session. This situation could lead to the onset of overtraining syndrome (OTS), where the patient experiences an unexplained decline in performance. The article reviews the muscular adaptation of COPD patients and the planned rehabilitation and emphasizes the concept that clinicians should structure the rehabilitation training program not in a linear fashion (constantly increasing loads), but in a wave-like fashion (scheduling some sessions with decreased loads). This organization could benefit the patient's performance, reducing the risk of OTS.

Indexed as

american thoracic societycopddiaphragmeuropean respiratory societyfev1inspiratory muscle trainingmaximal inspiratory pressureovertraining syndromerehabilitation training

Identifiers

PMID41822254
PMCPMC12976572

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.