Evidence map›Paper›PMID 41822323›Full record

ArticleWorld journal of oncology2026

Multi-Omics and Single-Cell Mendelian Randomization Reveal a Potential Role of

Zhi Chun Xue, Jing Lin, Jian Hui Wu, Zhi Wen Peng, Mei Yan Tang, Peng Liang, Hui Ling Chen, Gui Ju Fang, Qing Xue

Abstract read
In one paragraph

Article in World journal of oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhi Chun XueDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Jing LinDepartment of Emergency Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Jian Hui WuDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Zhi Wen PengDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Mei Yan TangDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Peng LiangDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Hui Ling ChenCollege of Marine Sciences, Ningde Normal University, Ningde, Fujian, China.
Gui Ju FangDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Qing XueDepartment of Respiratory and Critical Care Medicine, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed to evaluate the potential association between genetically predicted vanin-2 ( Methods: We integrated whole-blood expression quantitative trait loci (eQTL) data from eQTLGen, plasma protein quantitative trait loci (pQTL) data from deCODE, and LUAD genome-wide association study (GWAS) data from European-ancestry cohorts, together with differential expression analysis using GEPIA2, to identify candidate genes for subsequent single-cell eQTL (sc-eQTL) Mendelian randomization (MR) analysis. For the sc-eQTL analysis, Results: Bulk-level MR analysis showed that genetically predicted increases in Conclusions: Multi-omics and sc-eQTL MR analyses indicated that genetically predicted increases in

Indexed as

Lung adenocarcinomaMendelian randomizationResting NK cellssc-eQTLVNN2

Identifiers

PMID41822323
PMCPMC12978397

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.