Evidence map›Paper›PMID 41822702›Full record

ArticleFrontiers in gastroenterology (Lausanne, Switzerland)2024

Multiparametric quantitative MRI of healthy adult pancreas: correlations with gender and age.

Lixia Wang, Lu Liang, Jiyang Zhang, Chaowei Wu, Yang Zhou, Yang Yu, Chen Zhang, Christie Y Jeon, Tao Jiang, Srinivas Gaddam and 4 more

Abstract read
In one paragraph

Article in Frontiers in gastroenterology (Lausanne, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lixia WangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Lu LiangRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jiyang ZhangRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Chaowei WuBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Yang ZhouRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Yang YuRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Chen ZhangMR Scientific Marketing, Siemens Healthineers Ltd, Beijing, China.
Christie Y JeonDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Tao JiangRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Srinivas GaddamKarsh Division of Gastroenterology and Hepatology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Stephen J PandolDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Qi YangRadiologic Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The pancreas plays an important role in the nutrition and metabolism of the whole body. Many disease processes including obesity, diabetes mellitus (DM), acute or chronic pancreatitis, and pancreatic carcinoma result in abnormality of pancreas morphology and function. Magnetic resonance imaging (MRI) provides quantitative parameters including T1, T2, and apparent diffusion coefficient (ADC) values for evaluating normal and abnormal pancreas. Based on the normal range of these quantitative parameters, pancreatic abnormality could be detected early. However, the range and the relationship of T1, T2, and ADC values with gender and age groups using the same dataset have not been explored. Purpose: To establish the ranges of MRI tissue and functional parameters, including T1, T2, and ADC values, in healthy adult pancreas and their correlations with gender, subregion, and age. Materials and methods: The T1, T2, and ADC values of healthy pancreas in 86 adults were measured using a 3.0-T MRI scanner. The average T1, T2, and ADC values were obtained in the whole pancreas and subregions (head, neck, body, and tail). Their correlations with gender and age were investigated. Results: The T1, T2, and ADC values of the whole pancreas from all subjects were 870.07 ± 61.86 ms, 44.07 ± 6.14 ms, and 1.072 ± 0.212 × 10 Conclusion: This study established the normal ranges of T1, T2, and ADC. We found that T2 is different between men and women, and T1, T2, and ADC are age-dependent. These results could be useful for quantitative MRI of pancreatic disease.

Indexed as

apparent diffusion coefficientmagnetic resonance imagingpancreasquantitative parametersT1 valueT2 value

Identifiers

PMID41822702
PMCPMC12952309

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.