Evidence map›Paper›PMID 41822762›Full record

ReviewHealth science reports2026

Hypertension as a Predictor of Ovarian Cancer Risk: A Systematic Review and Meta-Analysis.

Abdur Rahim, Aftab Ullah, Wahby Mohammed Babaresh, Zakiullah, Kayam Naveen Kumar, Saikumar Gadidala, Zia Ul Hassan, Bushra Sajjad, Amogh Verma, Ranjana Sah and 1 more

Abstract readReview
In one paragraph

Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdur RahimDepartment of Pharmacy CECOS University Peshawar Pakistan.
Aftab UllahDepartment of Pharmacy University of Peshawar Khyber Pakhtunkhwa Pakistan.
Wahby Mohammed BabareshFaculty of Pharmacy University of Aden Aden Yemen.ORCID https://orcid.org/0009-0009-2325-9609
ZakiullahDepartment of Pharmacy University of Peshawar Khyber Pakhtunkhwa Pakistan.ORCID https://orcid.org/0000-0001-7932-9498
Kayam Naveen KumarClinical Research, National Institute of Pharmaceutical Education and Research Chandigarh Punjab India.
Saikumar GadidalaDepartment of Pharmacy Practice National Institute of Pharmaceutical Education and Research Guwahati India.
Zia Ul HassanCardiology Ward, Hayat Medical Complex Hospital Peshawar Pakistan.
Bushra SajjadDepartment of Pharmacy University of Peshawar Khyber Pakhtunkhwa Pakistan.
Amogh VermaDepartment of Internal Medicine Rama Medical College Hospital and Research Centre Hapur Uttar Pradesh India.ORCID https://orcid.org/0000-0003-2499-4874
Ranjana SahDepartment of Paediatrics, Dr. D. Y. Patil Medical College Hospital and Research Centre Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University) Pune Maharashtra India.ORCID https://orcid.org/0009-0009-8332-6391
Rachana MehtaClinical Microbiology, RDC, Manav Rachna International Institute of Research and Studies Faridabad Haryana India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Ovarian cancer is a primary contributor to cancer-related deaths among women and holds a position among the most common gynecological malignancies worldwide. While hypertension has been identified as a potential risk factor for various cancers, its association with ovarian cancer remains inconclusive. This systematic review and meta-analysis synthesized data from observational studies to provide light on the association between hypertension and the risk of ovarian cancer. Methods: This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and secured registration with the PROSPERO under the identifier CRD42025636649. A systematic literature search of PubMed, Embase, and Web of Science was conducted to identify observational studies published through December 10, 2024. Risk ratios (RRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Heterogeneity was assessed using the Results: Out of 2686 articles identified, 11 studies with a total of 2,523,751 participants met the inclusion criteria. There was a risk ratio (RR) of 1.06 (95% CI, 0.96-1.20) for ovarian cancer in patients with hypertension, and considerable heterogeneity was noted ( Conclusion: There is no statistically significant association between high blood pressure and the risk of ovarian cancer, according to this meta-analysis. To confirm these results, additional research utilizing larger participant groups and robust study designs is essential.

Indexed as

hypertensionmeta‐analysisovarian cancersystematic review

Identifiers

PMID41822762
PMCPMC12975656

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.