Trial reportJournal of the American Heart Association2026
Serum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.
Trial report in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03528031 (Habitual Diet and Avocado Trial), which is not on this map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Habitual Diet and Avocado Trial
Who cites it
1 citing paper in PubMed.
- The Habitual Diet and Avocado Trial (HAT): A Collaborative Multicenter Model for Large-Scale, Privately Funded Nutrition Research Consortia.Current developments in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAvocado consumption has been associated with improvements in diet quality and cardiometabolic risk factors, but effects on serum metabolite profiles remain underexplored.
methodsSecondary analysis was conducted using untargeted metabolomics to assess fasting serum metabolite profiles at baseline (preintervention) and 6 months (postintervention) in a subset of participants with abdominal obesity from the HAT (Habitual Diet and Avocado Trial), who were randomized to the avocado group (n = 120; 70% women; 49 ± 13 years of age; body mass index 33.1 ± 5.7 kg/m
resultsPlasma low-density lipoprotein cholesterol (-6%), systolic (-3%), and diastolic (-2%) blood pressure decreased, whereas visceral adipose tissue volume increased (3%) postintervention (all
conclusionsAvocado intake was associated with subtle shifts in serum metabolites related to lipid, carbohydrate, and amino acid metabolism, with weak effects on visceral adipose tissue volume, plasma triglycerides, and total cholesterol concentrations. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03528031.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.