Evidence mapPaperPMID 41824113Full record

ArticleLasers in medical science2026

Effects of photobiomodulation on human dental pulp stem cells treated with a bone xenograft: An in vitro study.

Priscilla Pelaez-Cruz, Pia Lopez-Jornet, Eduardo Pons-Fuster

Abstract read
In one paragraph

Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Priscilla Pelaez-CruzUniversity of Murcia, Murcia, Spain.
Pia Lopez-JornetUniversity of Murcia, Murcia, Spain. majornet@um.es.
Eduardo Pons-FusterUniversity of Murcia, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiocompatibility between bone cells and biomred for the process of osteogenesis. The aim of this study was to assess the effect of Photobiomodulation (PBM) in vitro on dental pulp stem cells (DPSCs) treated with Bio-Oss® (BO) bone substitute xenograft.

methodsDPSC cultures were obtained from third molars extracted from healthy volunteers and characterized by flow cytometry. The effects of PBM (5, 7, or 10 J/cm

resultsPBM restored the lost migration ability of DPSCs treated with BO; however, this combined therapy was associated with significantly lower levels of DPSC viability, alkaline phosphatase expression, and mineralization compared to controls.

conclusionPBM therapy did not improve the biocompatibility of DPSCs treated with BO bone substitute. The effect of interaction between these treatments seemed to be cytotoxic to DPSCs. Our results suggest that the interaction between BO and PBM therapy could impair bone regeneration.

Indexed as

Bone SubstitutesDental PulpLow-Level Light TherapyMineralsStem CellsAlkaline PhosphataseBone RegenerationCell MovementCells, CulturedCell SurvivalHeterograftsHumansOsteogenesisAlkaline PhosphataseBio-OssBone SubstitutesMineralsBiocompatibilityBone regenerationDental pulp stem cellsPhotobiomodulation

Identifiers

PMID41824113
PMCPMC12987799

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.