ArticleObesity surgery2026
Effects of Metabolic Bariatric Surgery on Weight Loss and Diabetes Remission Over 10 Years: A Network Meta-Analysis of Randomized Controlled Trials.
Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeThe long-term effects of metabolic bariatric surgery (MBS) on weight loss and diabetes remission over 10 years remain incompletely characterized. This network meta-analysis aimed to compare the outcomes of various types of MBS with those of medical therapy.
methodsPubMed and EMBASE were searched from inception to September 30, 2025, for randomized clinical trials (RCTs) with ≥ 10 years of follow-up comparing MBS and medical therapy in adults with obesity or type 2 diabetes. A random-effects model was applied.
resultsTen RCTs including 1004 participants were analyzed. Procedures assessed included Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), biliopancreatic diversion with duodenal switch (BPD/DS), and adjustable gastric banding (AGB). All procedures except AGB resulted in significantly greater percentage total weight loss than medical therapy, ranging from SG (mean difference [MD] = 17.73%; 95% CI, 6.96–28.50) to RYGB (MD = 20.18%; 95% CI, 11.18–29.18) and BPD/DS (MD = 28.87%; 95% CI, 19.80-37.93). A similar gradient (medical therapy < AGB < SG < RYGB < BPD/DS) was observed for reductions in body weight and BMI. Although only BPD/DS (odds ratio = 24.91; 95% CI, 1.19–519.94) achieved a statistically significant advantage over medical therapy in diabetes remission, other procedures also demonstrated a potential benefit.
conclusionsOver 10 years of follow-up, most MBS procedures were associated with greater weight loss than medical therapy, while only BPD/DS achieved a statistically significant improvement in diabetes remission.
Indexed as
Identifiers
41824260What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.