Evidence map›Paper›PMID 41824879›Full record

SynthesisMedicine2026

T-cell lymphoblastic lymphoma of the breast: A retrospective observational study and literature review.

Wei Bian, Jun Yuan, Yufeng Fei, Jinjuan Feng, Xu Zhang, Sili Jin, Yi Yang

Abstract readObservational StudySystematic Review
In one paragraph

Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei BianDepartment of Radiology, Jiaxing Maternity and Child Health Care Hospital, College of Medicine, Jiaxing University, Jiaxing Women and Children's Hospital Affiliated to Wenzhou Medical University, Jiaxing, China.ORCID 0000-0001-9590-7649
Jun YuanDepartment of Pathology, Jiaxing Maternity and Child Health Care Hospital, College of Medicine, Jiaxing University, Jiaxing Women and Children's Hospital Affiliated to Wenzhou Medical University, Jiaxing, China.
Yufeng FeiDepartment of Radiology, Jiaxing Maternity and Child Health Care Hospital, College of Medicine, Jiaxing University, Jiaxing Women and Children's Hospital Affiliated to Wenzhou Medical University, Jiaxing, China.
Jinjuan FengDepartment of Radiology, Ningbo City Yinzhou District Third Hospital, China.
Xu ZhangBreast Tumor Center, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sili JinDepartment of Breast, Jiaxing Maternity and Child Health Care Hospital, College of Medicine, Jiaxing University, Jiaxing Women and Children's Hospital Affiliated to Wenzhou Medical University, Jiaxing, China.
Yi YangDepartment of Breast, Jiaxing Maternity and Child Health Care Hospital, College of Medicine, Jiaxing University, Jiaxing Women and Children's Hospital Affiliated to Wenzhou Medical University, Jiaxing, China.

Funding

Livelihood Science and Technology Innovation Research 2022AD30095
6 · The paper itself

Abstract

This study aims to explore the diagnosis and treatment of T-cell lymphoblastic lymphoma (T-LBL) of the breast. We retrospectively analyzed the clinical data of a patient with breast T-LBL jointly managed by our hospital and Ruijin Hospital, Shanghai. A systematic literature review was conducted across PubMed, Web of Science, Embase, Cochrane Library, China Biomedical Literature Database, China national knowledge infrastructure, Wanfang, and Wipro databases up to May 10, 2024, using Boolean operators (e.g., ("T-cell lymphoblastic lymphoma" OR "T-LBL") AND ("breast" OR "mammary")). Including our case, 11 patients were studied. All were female (mean age 31.81 ± 11.97 years). Five cases involved both breasts, 6 were unilateral. Ten cases had extramammary involvement. Immunohistochemistry was positive for both terminal deoxynucleotidyl transferase and cluster of differentiation (CD3) in 9 breast lesions. Imaging included ultrasound (n = 6), mammography (n = 6), magnetic resonance imaging (n = 2), and positron emission tomography-computed tomography (n = 2). Most patients (n = 10) received chemotherapy, with some supplemented by radiotherapy and intrathecal prophylaxis. Breast T-LBL is exceedingly rare. Accurate diagnosis is crucial for management. Future prospective studies are needed to optimize diagnostic and therapeutic strategies.

Indexed as

Breast NeoplasmsPrecursor T-Cell Lymphoblastic Leukemia-LymphomaAdultChinaFemaleHumansMagnetic Resonance ImagingMiddle AgedRetrospective StudiesYoung Adultbreastlymphoblasticlymphomanon-HodgkinT-cell

Identifiers

PMID41824879
PMCPMC12991768

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.