Evidence mapPaperPMID 41826439Full record

Observational studyScientific reports2026

Clinical characteristics, disease activity and psychosocial burden of axial spondyloarthritis in Jordan: a multicenter cross-sectional study.

Fatima Alnaimat, Omar Hamdan, Moayad Shaf'ei, Zaid Al-Ghazawi, Ayman AbuHelal, Ahmad Odeh, Khaldoon M Alawneh

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatima AlnaimatDepartment of Internal Medicine, Division of Rheumatology, The University of Jordan, Amman, 11942, Jordan. f.naimat@ju.edu.jo.ORCID http://orcid.org/0000-0002-5574-2939
Omar HamdanSchool of Medicine, University of Jordan, Amman, 11942, Jordan.ORCID http://orcid.org/0009-0008-0442-0578
Moayad Shaf'eiDepartment of Special Surgery, School of Medicine, The University of Jordan, Amman, 11942, Jordan.ORCID http://orcid.org/0000-0003-1587-9911
Zaid Al-GhazawiSchool of Medicine, University of Jordan, Amman, 11942, Jordan.ORCID http://orcid.org/0000-0002-4032-7636
Ayman AbuHelalDepartment of Internal Medicine, Division of Rheumatology, The University of Jordan, Amman, 11942, Jordan.ORCID http://orcid.org/0009-0008-2294-2695
Ahmad OdehSchool of Medicine, University of Jordan, Amman, 11942, Jordan.ORCID http://orcid.org/0009-0007-1264-0151
Khaldoon M AlawnehDepartment of Internal Medicine, Division of Rheumatology, School of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.ORCID http://orcid.org/0000-0001-5505-3183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Axial spondyloarthritis (AxSpA) is a chronic inflammatory condition of the spine and sacroiliac joints, associated with a considerable functional and psychosocial burden. This study aimed to investigate the interplay between disease activity and patient-reported outcomes, specifically focusing on how psychosocial factors and functional status serve as predictors of disease severity in Jordanian patients with AxSpA. We conducted a cross-sectional study at two tertiary hospitals in Jordan, including patients diagnosed according to the Assessment of SpondyloArthritis International Society (ASAS) criteria. A total of 79 patients were analyzed, with a mean age of 41.1 ± 11.9 years and a significant diagnostic delay of 5.7 ± 6.1 years. Sixty-seven were diagnosed with ankylosing spondylitis (AS), and twelve with non-radiographic AxSpA (nr-axSpA). Most patients were current smokers (53.2%), and more than half of the patients were retired or unemployed. Notable psychosocial burden was observed according to the Patient Health Questionnaire-9 (PHQ-9) questionnaire, with over half of the patients experiencing depressive symptoms and one-fifth screening positive for fibromyalgia according to the Fibromyalgia Rapid Screening Tool (FiRST). Using the Ankylosing Spondylitis Disease Activity Score (ASDAS), a majority of patients demonstrated high (51.9%) or very high (29.1%) disease activity. Male patients and those with higher ASQOL scores (worse quality of life) were significantly more likely to have very high disease activity. In patients receiving TNF inhibitors, NLR maintained the highest discriminatory ability, with an AUC of 0.676 (95% CI: 0.517–0.834). Significant diagnostic delays, smoking prevalence, work disability, and psychological burden were observed. Longitudinal studies remain essential to confirm these findings and better assess disease progression and treatment outcomes.

Indexed as

Axial SpondyloarthritisAdultCost of IllnessCross-Sectional StudiesDepressionFemaleHumansJordanMaleMiddle AgedQuality of LifeSeverity of Illness IndexSpondylitis, AnkylosingAnkylosing SpondylitisAxial SpondyloarthritisNon-Radiographic Axial Spondyloarthritis

Identifiers

PMID41826439
PMCPMC13111697

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.