Evidence map›Paper›PMID 41827410›Full record

ReviewJournal of clinical medicine2026

Burning Issues/Hot Topics: The Charcot Foot.

Victoria E L Milbourn, Ava Khoshnaghsh, Michael E Edmonds, Nina L Petrova

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victoria E L MilbournDepartment of Rehabilitation Medicine, Amsterdam University Medical Centre, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0009-0004-7416-956X
Ava KhoshnaghshGuy's, King's and St Thomas' School of Medicine, Faculty of Life Sciences and Medicine, King's College London, London SE5 9RS, UK.ORCID 0009-0006-1849-4549
Michael E EdmondsMike Edmonds Foot Unit, King's College Hospital National Health Service Foundation Trust, London SE5 9RS, UK.ORCID 0000-0002-8931-0069
Nina L PetrovaMike Edmonds Foot Unit, King's College Hospital National Health Service Foundation Trust, London SE5 9RS, UK.

Funding

The European Union's Horizon 2020 Marie Skłodowska-Curie programme Grant Agreement No. 101073533; DIALECT
6 · The paper itself

Abstract

Charcot neuro-osteoarthropathy remains one of the most serious complications of diabetic neuropathy, with the potential for rapid progression to deformity, ulceration and limb-threatening outcomes. The earliest signs and symptoms are often subtle and easily missed, yet early recognition provides a narrow window of opportunity to prevent irreversible structural change. Contemporary diagnostic pathways are underpinned by close clinical observation and correlation of bedside findings with detailed imaging analysis, enabling earlier identification of active disease before collapse occurs. This article provides a comprehensive overview of the Charcot foot, integrating clinical presentation, differential diagnosis and current approaches to investigation and management. It also highlights the challenges of monitoring disease activity over time, including remission and relapse, and the importance of timely specialist referral and multidisciplinary management. By reinforcing structured assessment and targeted intervention, this review aims to support consistent, evidence-informed care for people affected by Charcot neuro-osteoarthropathy.

Indexed as

Charcot neuro-osteoarthropathyclinical managementdiabetic neuropathy

Identifiers

PMID41827410
PMCPMC12986205

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.