Evidence map›Paper›PMID 41827438›Full record

ArticleJournal of clinical medicine2026

Effectiveness and Safety of the Combination of Paracetamol 1000 mg and Ibuprofen 300 mg Versus Ibuprofen 600 mg in Monotherapy in Acute Low Back Pain: Results from a Phase IV Randomized Study.

Michal Harasymczuk, Antimo Moretti, Martina Barcaroli, Elisa Quarchioni, Ajona Tulipano, Adriano Nicolotti, Michela Procaccini, Enrica Salvatori, Agnese Cattaneo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michal HarasymczukTraumatology, Orthopedics, Hand Surgery Department, Dega Orthopedics Institute, Poznan University of Medical Sciences, 60-812 Poznan, Poland.ORCID 0000-0002-8787-643X
Antimo MorettiMultidisciplinary Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-4598-2891
Martina BarcaroliGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.
Elisa QuarchioniGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.
Ajona TulipanoGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.ORCID 0009-0006-2881-493X
Adriano NicolottiGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.ORCID 0009-0000-0082-1771
Michela ProcacciniGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.
Enrica SalvatoriGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.
Agnese CattaneoGlobal Medical Department, Angelini Pharma S.p.A., 00181 Rome, Italy.

Funding

Angelini Pharma S.p.A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

combined therapyeffectivenessibuprofen in monotherapylow back painparacetamol and ibuprofensafety

Identifiers

PMID41827438
PMCPMC12985560

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.