Evidence map›Paper›PMID 41827870›Full record

ArticleCells2026

Glycyrrhizic Acid Attenuates Aβ

S Amrutha, Thottethodi Subrahmanya Keshava Prasad, Prashant Kumar Modi

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Frontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S AmruthaCenter for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0001-7696-0903
Thottethodi Subrahmanya Keshava PrasadCenter for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0002-6206-2384
Prashant Kumar ModiCenter for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0002-4817-3379

Funding

Yenepoya (Deemed to be University) YU/Seed grant/134-2022
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a catastrophic neurodegenerative disorder marked by progressive decline of cognitive function, memory loss, and neuronal death. Its pathology is characterized by the formation of extracellular amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles from tau hyperphosphorylation. Despite extensive research, current treatments are limited to symptomatic relief and are associated with significant side effects. This accentuates the critical need for alternative therapeutic strategies with potent neuroprotective effects and minimal toxicity. This study investigates the neuroprotective potential of glycyrrhizic acid, as the precise molecular mechanisms by which it might improve AD pathology remain poorly understood. Using an Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesGlycyrrhizic AcidOxidative StressPeptide FragmentsSignal TransductionSynapsesApoptosisBiomarkersHumansMitochondriaNeuronsNeuroprotective AgentsAmyloid beta-Peptidesamyloid beta-protein (1-42)BiomarkersGlycyrrhizic AcidNeuroprotective AgentsPeptide Fragmentsamyloid-betaapoptosisglycyrrhizic acidmitochondrial dysfunctionneuroprotection

Identifiers

PMID41827870
PMCPMC12984613

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.