Evidence mapPaperPMID 41828379Full record

ArticleInternational journal of molecular sciences2026

Connexin 43 and Pannexin 1 in Renal Cell Populations in Diabetic Kidney Disease.

Marinela Jelinčić Korčulanin, Anita Racetin, Nikola Pavlović, Ivo Jeličić, Merica Glavina Durdov, Monika Andrzejewska, Leo Jerčić, Ivana Bočina, Nives Kević, Ivana Restović and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marinela Jelinčić KorčulaninDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.
Anita RacetinDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.
Nikola PavlovićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-3452-389X
Ivo JeličićRenal Unit, Clinical Hospital of Split, 21000 Split, Croatia.
Merica Glavina DurdovDepartment of Pathology, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0002-8292-9854
Monika AndrzejewskaDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0009-0003-7265-4150
Leo JerčićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.
Ivana BočinaDepartment of Biology, Faculty of Science, University of Split, 21000 Split, Croatia.ORCID 0000-0002-3868-0828
Nives KevićDepartment of Biology, Faculty of Science, University of Split, 21000 Split, Croatia.ORCID 0000-0001-7167-5230
Ivana RestovićDepartment of Teacher Education, University of Split Faculty of Humanities and Social Sciences, 21000 Split, Croatia.ORCID 0000-0002-2970-9852
Katarina VukojevićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-2182-2890
Patricija BajtDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.
Karla SvagušaDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0001-9572-6362
Natalija FilipovićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-8943-4109

Funding

Croatian Science Foundation HRZZ-IP-2022-10-7321
6 · The paper itself

Abstract

We studied the expression of connexin 43 (Cx43) and pannexin 1 (PANX1) in different cellular populations of the kidneys of diabetic mice and diabetic and non-diabetic patients, to evaluate their role as potential therapeutic targets in diabetic kidney disease (DKD). A combination of a low dose of streptozotocin and a high-fat diet (HFD) was used to induce a type 2 diabetes model (DM2) in mice. Kidney tissues from diabetic (

Indexed as

Connexin 43ConnexinsDiabetic NephropathiesKidneyNerve Tissue ProteinsAnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Diet, High-FatFemaleHumansMaleMiceMice, Inbred C57BLPericytesPodocytesConnexin 43ConnexinsNerve Tissue ProteinsPANX1 protein, humanPanx1 protein, mousecell populationsconnexin 43diabetic nephropathypannexin 1

Identifiers

PMID41828379
PMCPMC12984592

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.