Evidence mapPaperPMID 41828632Full record

SynthesisInternational journal of molecular sciences2026

Systematic Review: Long-Read Sequencing in Algal Studies.

Kakima Kastuganova, Alyamdar Askerov, Attila Szabó, Natasha S Barteneva

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kakima KastuganovaDepartment of Biology, School of Sciences and Humanities, Nazarbayev University, Astana 010000, Kazakhstan.
Alyamdar AskerovDepartment of Biology, School of Sciences and Humanities, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0009-0001-2591-6483
Attila SzabóDepartment of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, 75007 Uppsala, Sweden.
Natasha S BartenevaDepartment of Biology, School of Sciences and Humanities, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-8109-1754

Funding

Ministry of High Education and Sciences, Kazakhstan AP26104995Nazarbayev University FDCRGP grant #SSH2024005
6 · The paper itself

Abstract

Long-read sequencing (LRS) has transformed life science research by introducing third-generation sequencing (TGS) platforms applicable across various research fields, including environmental sciences. In the past decade, LRS platforms have been utilized to extensively study algal systems by improving genomic approaches such as metabarcoding, chromosome-level genome and pangenome assemblies, as well as providing new insights into algae-associated microbiomes and host-symbiont interactions. This review aims to discuss recent advancements in LRS in algal research. To achieve this aim, a systematic review was conducted according to the PRISMA 2020 guidelines and across three electronic databases (Web of Science, Scopus, and Google Scholar), with additional citation searching for relevant studies in four key algal research areas: metabarcoding, genomics, pangenomics, and host-symbionts interactions. Following the inclusion and exclusion criteria, only 51 studies were selected for this review. Throughout the review, we summarize the challenges of short-read sequencing (SRS) and discuss how LRS platforms address these challenges in algal studies. Furthermore, we discuss the future of LRS and explore how artificial intelligence (AI) can advance research on algal biology and ecology.

Indexed as

High-Throughput Nucleotide SequencingGenomicsMicrobiotaSymbiosis16S/18S rRNA genealgal host–bacterial symbiosisalgal microbiomelong-read sequencingmetabarcodingnanopore sequencingONTPacBiopangenome

Identifiers

PMID41828632
PMCPMC12985685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.