ArticleInternational journal of molecular sciences2026
Tubular Epithelia-Specific Deletion of MCP-1 Does Not Afford Protection Against Adriamycin-Induced Kidney Injury.
Corry D Bondi, Hannah L Hartman, Josie L Gilbert, Joy A Stewart, Dennis R Clayton, Roderick J Tan
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
6 authors.
Corry D BondiDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.
Hannah L HartmanDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.
Josie L GilbertDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.
Joy A StewartDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.
Dennis R ClaytonDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.
Roderick J TanDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 152671, USA.ORCID 0000-0003-1012-1722 Funding
Resource Development CoreU54DK137329 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2025 to 2025
$953kRenal Myofibroblast: Origins, Activation and FateR01DK064005 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2003 to 2005
$740kEffect of Renal Nerves on Chronic Kidney DiseaseR01DK131991 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2025 to 2025
$478kAmerican Society of Nephrology Carl W. Gottschalk Research Scholar Grant N/ABLRD VA I01 BX005680Department of Veterans Affairs Merit Award I01BX005680National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases K01DK124357National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases R01DK064005National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases R01DK131991NIDDK NIH HHS R01 DK064005NIDDK NIH HHS R01 DK131991NIDDK NIH HHS U54 DK137329NIH HHS 1S10OD028596NIH HHS P30DK079307Pittsburgh Center for Kidney Research U54DK137329
6 · The paper itselfAbstract
The increasing global burden of chronic kidney disease (CKD) magnifies an urgent need to find treatable targets. Monocyte chemoattractant protein-1 (MCP-1/CCL2) is a chemokine secreted by kidney tubular epithelia in response to a variety of stimuli. To better understand the effects of tubular MCP-1 in response to kidney injury, we generated tubular epithelia-specific MCP-1 knockout mice (KO; Pax8-
Indexed as
Chemokine CCL2DoxorubicinKidney TubulesAnimalsGene DeletionMaleMiceMice, KnockoutCcl2 protein, mouseChemokine CCL2DoxorubicinCCL2chemokinechronic kidney diseaseglomerular injurytubular injury
Identifiers
PMID41828647
PMCPMC12986468
What Socratic holds
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