ArticleMolecules (Basel, Switzerland)2026
Microencapsulated Hydroxyapatite-TEGDMA Systems for Self-Healing in Dental Applications.
Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of microcapsules for the controlled release of active substances offers an innovative strategy in restorative dentistry, expanding the possibilities beyond traditional methods. In this study, microcapsules loaded with triethylene glycol dimethacrylate (TEGDMA) and different concentrations of hydroxyapatite (HAP)-0%, 5%, 10%, 15%, and 20%, referred to as M0, M5, M10, M15, and M20-were synthesized through in situ polymerization within an oil-in-water emulsion. Their morphology, size, and nanostructure were examined using scanning electron microscopy (SEM) and atomic force microscopy (AFM). Fourier-transform infrared spectroscopy (FTIR) confirmed the presence of characteristic chemical bonds, whereas high-performance liquid chromatography (HPLC) quantified residual TEGDMA monomer. Low-field nuclear magnetic resonance (NMR) further confirmed the presence and the distribution of the liquid healing agent inside the microcapsules. The analyses indicated that microcapsules incorporating 20% hydroxyapatite exhibited superior structural organization and improved shell integrity, highlighting their potential in the remineralization processes. Overall, these results support the potential of HAP-TEGDMA microcapsules for incorporation into dental composites to facilitate microcrack repair and promote dental tissue regeneration.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.