ArticleMolecules (Basel, Switzerland)2026
Coffee Silverskin Supplementation Alleviates High-Glucose-Diet-Induced Obesity by Modulating Lipogenic Gene Expression in
Emily Schifano, Paola Zinno, Fausta Natella, Laura Pompa, Erica Sonaglia, Sophia Spaziani, Mohammad Sharbaf, Francesco Esposito, Teresa Cirillo, Jonathan Squillante and 6 more
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
16 authors.
Emily SchifanoDepartment for Well-Being, Health and Environmental Sustainability-BeSSA, Sapienza University of Rome, Via Della Fontanelle, 02100 Rieti, Italy.
Paola ZinnoInstitute for Animal Production System in the Mediterranean Environment (ISPAAM), National Research Council, Piazzale Enrico Fermi 1, 80055 Portici, Italy.ORCID 0000-0001-9446-7979 Fausta NatellaResearch Centre for Food and Nutrition, CREA (Consiglio per la Ricerca in Agricoltura e L'analisi Dell'economia Agraria), Via Ardeatina 546, 00178 Rome, Italy.ORCID 0000-0002-1999-9817 Laura PompaDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Erica SonagliaDepartment of Chemical Engineering Materials and Environment, Sapienza University of Rome, Via Eudossiana 18, 00184 Rome, Italy.
Sophia SpazianiDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Mohammad SharbafDepartment of Chemical Engineering Materials and Environment, Sapienza University of Rome, Via Eudossiana 18, 00184 Rome, Italy.
Francesco EspositoDepartment of Agricultural Sciences, University of Naples Federico II, Piazza Carlo di Borbone 1, 80055 Portici, Italy.ORCID 0000-0001-7781-2558 Teresa CirilloDepartment of Agricultural Sciences, University of Naples Federico II, Piazza Carlo di Borbone 1, 80055 Portici, Italy.
Jonathan SquillanteDepartment of Agricultural Sciences, University of Naples Federico II, Piazza Carlo di Borbone 1, 80055 Portici, Italy.
Giuseppe MaglioneInstitute for Animal Production System in the Mediterranean Environment (ISPAAM), National Research Council, Piazzale Enrico Fermi 1, 80055 Portici, Italy.ORCID 0000-0002-6495-7739 Patrizia ManciniDepartment of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0003-0556-2056 Antonio AngeloniDepartment for Well-Being, Health and Environmental Sustainability-BeSSA, Sapienza University of Rome, Via Della Fontanelle, 02100 Rieti, Italy.
Maria Laura SantarelliDepartment of Chemical Engineering Materials and Environment, Sapienza University of Rome, Via Eudossiana 18, 00184 Rome, Italy.ORCID 0000-0002-3261-6024 Chiara DevirgiliisResearch Centre for Food and Nutrition, CREA (Consiglio per la Ricerca in Agricoltura e L'analisi Dell'economia Agraria), Via Ardeatina 546, 00178 Rome, Italy.ORCID 0000-0002-7114-7726 Daniela UccellettiDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0001-6841-8129 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Coffee silverskin (CSS), the major by-product of coffee roasting, is reported to contain bioactive compounds, including xanthines and polyphenols, showing promising potential for food and nutraceutical applications. This study investigated the beneficial effects of CSS hydroalcoholic extracts, which were chemically characterized by Attenuated Total Reflectance-Fourier-Transform Infrared Spectroscopy and ElectroSpray Ionization tandem Mass Spectrometry, on
Indexed as
Caenorhabditis elegansDietary SupplementsGene Expression RegulationGlucoseLipogenesisObesityPlant ExtractsAnimalsAntioxidantsCaenorhabditis elegans ProteinsDisease Models, AnimalLipid MetabolismOxidative StressReactive Oxygen SpeciesAntioxidantsCaenorhabditis elegans ProteinsGlucosePlant ExtractsReactive Oxygen Speciescoffee silverskinlipid metabolismnematodenutritionobesityoxidative stress
Identifiers
PMID41828874
PMCPMC12986101
What Socratic holds
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