Anthocyanins Alleviate Persistent Corpus Luteum and Ovarian Quiescence in Beef Cows by Modulating Gut Microbiota and Reducing Granulosa Cell Apoptosis.

Jiandong Wang, Xue Zhang, Youli Yu, Yi Wu, Yanan Guo

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

The Impact of Oxidative Stress Imbalance on Ovarian Function and Its Mechanisms.International journal of general medicine · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiandong WangInstitute of Animal Science, Ningxia Academy of Agricultural and Forestry Sciences, Yinchuan 750002, China.ORCID 0000-0002-9207-5100

Xue ZhangCollege of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.

Youli YuInstitute of Animal Science, Ningxia Academy of Agricultural and Forestry Sciences, Yinchuan 750002, China.

Yi WuCollege of Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.

Yanan GuoInstitute of Animal Science, Ningxia Academy of Agricultural and Forestry Sciences, Yinchuan 750002, China.ORCID 0000-0001-7371-1637

Funding

Ningxia Beef Cattle Disease Early Warning and Prevention Technology Innovation Team (2023CXTD0011)

6 · The paper itself

Abstract

Persistent corpus luteum (PCL) and ovarian quiescence (OQ) are key manifestations of ovarian dysfunction (OD) that lead to reduced reproductive capacity in beef cattle, posing a serious challenge to the industry. Anthocyanins (ACNs) are known for their antioxidant properties. This study aimed to investigate the regulatory effects of ACNs on PCL and OQ and to explore the underlying mechanisms. Forty-eight beef cows diagnosed with both OQ and PCL were selected and continuously fed ACNs for 60 days. The results showed that the regulatory effects of ACNs were dose-dependent. A high dose of ACNs (ACNH) significantly increased the number of large follicles and reduced the occurrence of PCL. ACNH treatment significantly decreased serum progesterone (P4) levels and increased estradiol (E2) levels. Furthermore, ACNH reduced microbial diversity in OD cows but significantly increased the abundance of

Indexed as

anthocyaninsbeef cattlegut microbiotaovarian quiescencepersistent corpus luteumtranscriptomics

Identifiers

PMID41828969

DOI10.3390/ani16050762

PMCPMC12985109

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.