Evidence mapPaperPMID 41829914Full record

ArticleNutrients2026

Niacin Mitigates Cyclophosphamide-Induced Immunosuppression by Maintaining Intestinal Homeostasis and Regulating the HCAR2/NLRP3 and PTGS2/PGE2 Signaling Pathways.

Yixian Bai, Yifan Zhou, Guifa Wang, Yuanzheng Wang, Tongtong Li, Kening Zhang, Huaqi Zhang, Hui Liang

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yixian BaiDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.ORCID 0009-0008-0852-5289
Yifan ZhouThe First Clinical College, Ningxia Medical University, Yinchuan 750004, China.
Guifa WangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, 308 Ningxia Road, Qingdao 266021, China.
Yuanzheng WangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Tongtong LiDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Kening ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Huaqi ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Hui LiangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.ORCID 0000-0002-0675-6963

Funding

Key technology research and industrialization demonstration projects in Qingdao City No. 25-1-1-gjgg-71-nshNational Nature Science Foundation of China No. 82273626Shandong Provincial Natural Science Foundation No. ZR2024MH073
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cyclooxygenase 2CyclophosphamideIntestinesNiacinNLR Family, Pyrin Domain-Containing 3 ProteinReceptors, G-Protein-CoupledSignal TransductionAnimalsCytokinesDinoprostoneHomeostasisImmunosuppression TherapyIntestinal MucosaMaleMiceMice, Inbred BALB CCyclooxygenase 2CyclophosphamideCytokinesDinoprostoneHcar2 protein, mouseNiacinNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousePtgs2 protein, mouseReceptors, G-Protein-Coupledcyclophosphamidegut microbiotaimmunomodulatoryintestinal barrierniacin

Identifiers

PMID41829914
PMCPMC12986744

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.