Evidence mapPaperPMID 41830076Full record

ReviewJournal of neuromuscular diseases2026

Expanding repeats, expanding impact: Somatic instability in myotonic dystrophy type 1.

Thomas D Hoekman, Nehaa Kp Ponraj, Diana Shabshai, Sarah A Cumming, Darren G Monckton, Derick G Wansink

Abstract readReview
In one paragraph

Review in Journal of neuromuscular diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas D HoekmanDepartment of Medical BioSciences, Radboud University Medical Center, Radboud Institute for Medical Innovation, Nijmegen, The Netherlands.ORCID 0009-0009-8916-3781
Nehaa Kp PonrajSchool of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0009-0002-9576-5753
Diana ShabshaiSchool of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Sarah A CummingSchool of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0002-0201-3660
Darren G MoncktonSchool of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0002-8298-8264
Derick G WansinkDepartment of Medical BioSciences, Radboud University Medical Center, Radboud Institute for Medical Innovation, Nijmegen, The Netherlands.ORCID 0000-0002-6773-8662

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disorder caused by a CTG

Indexed as

disease heterogeneitydisease progressiondisease severityDNA repairmismatch repairmyotonic dystrophyrepeat expansionsomatic instabilitytriplet repeat

Identifiers

PMID41830076
PMCPMC13438899

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.