Evidence map›Paper›PMID 41830200›Full record

ArticleJournal of neurotrauma2026

Behavioral Deficits and Cortical Network Dysfunction Following Repeated Mild Traumatic Brain Injuries.

Natalie J Pinkowski, Brandi R Hess, Johann M Pacheco, Devon S Hatcher, Myah McDonald, Adrienne N Swindle, Raycarlo Laboy Ramirez, Matthew Situ, Taha Abdeljawad, Carissa J Mehos and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Natalie J PinkowskiDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Brandi R HessDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Johann M PachecoDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Devon S HatcherDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Myah McDonaldDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.ORCID 0009-0001-8274-6345
Adrienne N SwindleDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Raycarlo Laboy RamirezDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Matthew SituDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Taha AbdeljawadDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Carissa J MehosDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Andrew R MayerMind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, New Mexico, USA.
Sam McKenzieDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Russell A MortonDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI SHUTTLEWORTH, CLAUDE W · 2015 to 2024
$22.7M
UPLIFT: UCLA Postdocs' Longitudinal Investment in Faculty TrainingK12GM106996 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CAREY, MICHAEL F, VILLANUEVA, CLAUDIO J · 2016 to 2025
$7.1M
Integrative Program in CNS Pathophysiology ResearchP30GM103400 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIU, KE JIAN · 2012 to 2016
$4.7M
University of New Mexico (UNM) Center for Brain Recovery and RepairP30GM159568 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Claude W Shuttleworth · 2025 to 2026
$3.4M
Initiative to Maximize Student Diversity at the University of New Mexico Health Sciences Center 2021T32GM144834 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Judy Lin Cannon, Bryce C Chackerian · 2022 to 2026
$2.7M
Spreading Depolarizations and Neuronal VulnerabilityR01NS106901 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Claude W Shuttleworth · 2018 to 2026
$2.5M
U-Rise at the University of New MexicoT34GM145428 · NIGMS · UNIVERSITY OF NEW MEXICO · PI Cristina D. Takacs-Vesbach · 2022 to 2026
$1.7M
NIGMS NIH HHS K12 GM106996NIGMS NIH HHS P20 GM109089NIGMS NIH HHS P30 GM103400NIGMS NIH HHS P30 GM159568NIGMS NIH HHS T32 GM144834NIGMS NIH HHS T34 GM145428NINDS NIH HHS R01 NS106901
6 · The paper itself

Abstract

Mild traumatic brain injury (mTBI) is a prevalent health concern, with more than 2.5 million cases occurring annually in the United States. Acute signs and symptoms of mTBIs may involve physical symptoms, as well as emotional, cognitive, and sleep-related issues. The underlying mechanisms of these symptoms remain elusive. Here, we describe that repeated closed skull mTBIs in mice are associated with acute behavioral deficits. We found that optogenetic-induced spreading depolarizations (SDs) are associated with similar behavioral deficits. Using

Indexed as

Behavior, AnimalBrain ConcussionCerebral CortexCortical Spreading DepressionNerve NetAnimalsMaleMiceMice, Inbred C57BLOptogeneticsbehavioral assessmentelectrophysiologyvascular reactivity

Identifiers

PMID41830200
PMCPMC13054653

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.