ArticleAging clinical and experimental research2026
Psoas muscle volume as a diagnostic indicator for sarcopenia: criteria development and comparison with traditional diagnostic approaches.
Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Dynapenic obesity: an actionable geriatric phenotype awaiting clinical translation in older adults.Aging clinical and experimental research · 2026Article
- Imaging without biology: limitations of CT-derived psoas muscle volume as a standalone diagnostic criterion for sarcopenia.Aging clinical and experimental research · 2026Article
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3 authors.
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Abstract
backgroundSarcopenia significantly impacts quality of life and increases the risk for various health issues. This study aims to establish a new, effective diagnostic criterion for sarcopenia based on psoas muscle volume (PV) using computed tomography (CT).
aimsWe analyzed the population distribution of psoas muscle volume (PV), assessed its correlation with ASM indices, and developed CT-based diagnostic criteria for sarcopenia.
methodsA total of 3,999 adults (2,085 men, 1,914 women; aged 22–89) who underwent abdominal CT and bioimpedance analysis (BIA) were included. Psoas muscle volume was automatically segmented using a deep-learning algorithm. Correlations with ASM indices were evaluated, and diagnostic criteria were established using (1) linear regression, (2) ROC analysis, and (3) T-score analysis referencing young, non-sarcopenic adults.
resultsThe distribution of PV indices peaked in the 30s and declined with age, more sharply in men. PV showed strong correlations with ASM indices, particularly the PV/BMI index, which demonstrated the highest diagnostic accuracy. T-score adjustment to -2.0 better matched known prevalence rates. DISCUSSION: This study proposes CT-based diagnostic criteria for sarcopenia using psoas muscle volume, demonstrating strong correlation with established indices. These findings support opportunistic screening via CT, offering a practical, population-wide tool for early sarcopenia detection.
conclusionsThis study uncovers the distribution of PV across age groups, noting a significant decline from the 30s to the 70s. This advancement in the objective diagnosis of sarcopenia via imaging positions abdomen CT scans as a potential diagnostic screening tool for low muscle mass compatible with sarcopenia.
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