Evidence mapPaperPMID 41833393Full record

ArticleAddiction (Abingdon, England)2026

The association between sleep disturbance and stimulant use: A cross-lagged examination.

Viviana E Horigian, Renae D Schmidt, Daniel J Feaster, Rui Duan, Sophia T Gonzalez, Kathryn Hefner, Dikla Shmueli-Blumberg, Ashley Vena, Landhing M Moran, Chloe A DiCamillo and 3 more

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Viviana E HorigianDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-3578-0014
Renae D SchmidtDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-0390-0712
Daniel J FeasterDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Rui DuanDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Sophia T GonzalezDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Kathryn HefnerThe Emmes Company, LLC, Rockville, MD, USA.
Dikla Shmueli-BlumbergRho, Inc., Durham, NC, USA.
Ashley VenaThe Emmes Company, LLC, Rockville, MD, USA.
Landhing M MoranCenter for the Clinical Trials Network, National Institute on Drug Abuse, National Institutes of Health, Gaithersburg, MD, USA.ORCID https://orcid.org/0000-0002-3122-634X
Chloe A DiCamilloDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Shirin ShafazandDepartment of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Susan TrossDepartment of Psychiatry, Columbia University, New York, NY, USA.
Judith FeinbergDepartments of Behavioral Medicine and Psychiatry & Medicine/Infectious Diseases, West Virginia University School of Medicine, Morgantown, WV, USA.

Funding

NIDA Clinical Trials Network: New York Node - Renewal-GY24UG1DA013035 · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2025 to 2025
$6.0M
The Florida Node Alliance of the National Drug Abuse Clinical Trials Network (CTN-121)UG1DA013720 · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2025 to 2025
$5.8M
West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve HealthU54GM104942 · WEST VIRGINIA UNIVERSITY · 2025 to 2025
$4.0M
NIDA NIH HHS 2UG1DA049436NIDA NIH HHS 2UG1DA04943601NIDA NIH HHS 75N95019D00013/N01DA-19-2250NIDA NIH HHS 75N95020D00012/N01DA-20-2251NIDA NIH HHS U54GM104942NIDA NIH HHS UG1DA013035NIDA NIH HHS UG1DA013720
6 · The paper itself

Abstract

BACKGROUND AND

aimsSleep disruptions increase the risk of substance misuse. Substance use-especially stimulants-can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).

designIn this secondary analysis, a Random Intercept Cross-Lagged Panel Model (RI-CLPM) was used to assess sleep disturbance and stimulant use over 8 weeks among participants with StUD.

settingUnited States of America.

participantsThe analysis included 793 participants with StUD enrolled across 3 randomized controlled trials in the National Institute on Drug Abuse's Clinical Trials Network (CTN): CTN-0037, CTN-0048 and CTN-0068. MEASUREMENTS: Self-reported sleep disturbance was harmonized as a binary indicator across trial measures at each week. Stimulant use days per week were captured by Timeline Follow Back. Baseline covariates included age, sex, race/ethnicity, employment status, presence of depressive symptoms, any psychiatric history, treatment arm and trial.

findingsSleep disturbance was associated with a higher average number of stimulant use days the following week [β = 0.15, 95% confidence interval (CI) = 0.09, 0.22, P < 0.001], and greater stimulant use was linked to increased odds of subsequent sleep disturbance (odds ratio = 1.20, 95% CI = 1.14, 1.26, P < 0.001).

conclusionsHigher-than-usual stimulant use appears to be associated with increased likelihood of sleep disturbance the following week, and vice versa.

Indexed as

Amphetamine-Related DisordersCentral Nervous System StimulantsSleep Wake DisordersSubstance-Related DisordersAdultFemaleHumansMaleMiddle AgedUnited StatesYoung AdultCentral Nervous System Stimulantsrandom‐intercept cross‐lagged panel modelsleepsleep disturbancesleep problemsstimulant usesubstance‐related disorderssubstance use

Identifiers

PMID41833393
PMCPMC13357745

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.