Evidence map›Paper›PMID 41833852›Full record

ReviewThe journal of pain2026

Single Session Behavioral Interventions for Chronic Pain A Systematic Review and Meta Analysis of Randomized Controlled Trials.

Maisa S Ziadni, Troy C Dildine, Karlyn A Edwards, Ashley Herrick, Dokyoung S You, Beth D Darnall

Abstract readReview
In one paragraph

Review in The journal of pain, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maisa S ZiadniDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, MC5596, Palo Alto, CA, 94304, USA. Electronic address: mziadni@stanford.edu.
Troy C DildineDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, MC5596, Palo Alto, CA, 94304, USA.
Karlyn A EdwardsDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Ashley HerrickDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, MC5596, Palo Alto, CA, 94304, USA.
Dokyoung S YouHealth Promotion Research Center, Stephenson Cancer Center, and Department of Family and Community Medicine, University of Oklahoma, Oklahoma, United States.
Beth D DarnallDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, MC5596, Palo Alto, CA, 94304, USA.

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
University of Pittsburgh Collaboration in Addiction Training Scholars (PittCATS) ProgramK12DA050607 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jane M. Liebschutz, Erin L Winstanley · 2020 to 2026
$3.2M
Single Session Pain Catastrophizing Class: Efficacy & Mechanisms for Reducing Opioid Use Among Chronic Pain PatientsK23DA047473 · NIDA · STANFORD UNIVERSITY · PI ZIADNI, MAISA · 2019 to 2023
$796k
Effect of pain catastrophizing on prescription opioid cravingK23DA048972 · NIDA · STANFORD UNIVERSITY · PI YOU, DOKYOUNG SOPHIA · 2019 to 2023
$758k
Using Human Centered Design to Tailor a Web-based Behavioral Treatment for Chronic Pain and Opioid Use DisorderK23DA063868 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Karlyn Ann Edwards · 2025 to 2026
$377k
NIDA NIH HHS K12 DA050607NIDA NIH HHS K23 DA047473NIDA NIH HHS K23 DA048972NIDA NIH HHS K23 DA063868NIDA NIH HHS T32 DA035165
6 · The paper itself

Abstract

Single session interventions (SSIs) for chronic pain are a novel and scalable intervention approach that are far less burdensome than typical 8-session behavioral treatments, and have demonstrated improvements in pain outcomes. Therefore, the current review focuses on systematically summarizing evidence from randomized controlled trials (RCTs) on behavioral SSIs for chronic pain. The review was prospectively registered (PROSPERO CRD42023447224), and the search strategy included seven electronic databases up until 11/2024. Title, abstract, and full text review was conducted with 17 RCTs identified and summarized. Eligible studies were RCTs testing a psychological SSI that targeted pain among adults with chronic pain. Study quality was analyzed using National Institute of Health (NIH)'s Quality Assessment Tool for RCTs. The review focused on synthesizing: 1) the main contents, mode, frequency and duration of interventions for patients with chronic pain; and 2) the effects of SSIs on psychological and physical outcomes. Overall, we found that various SSIs demonstrated efficacy in improving pain outcomes. Specifically, small but significant effects of SSIs were observed for pain intensity (Standardized mean difference [SMD]=0.17) and pain interference (SMD=0.27) compared to control conditions. SSIs also demonstrated significant reductions in pain catastrophizing, anxiety, and depression (SMD = 0.37, 0.29, and 0.25 respectively). Of the 17 RCTs, 13 (76%) had good internal validity, and 4 (24%) had fair internal validity. SSIs can be low burden and improve behavioral pain care access. Finally, we discuss design and methodology recommendations for future research on SSIs for chronic pain. PERSPECTIVE: Findings suggest that SSIs are generally effective in improving pain and other health outcomes across various types of chronic pain conditions. SSIs can be low burden and improve behavioral pain care access, especially in settings where longer-course behavioral treatments are infeasible or not offered.

Indexed as

Chronic paindigitalpsychological/behavioral interventionssingle-sessionsystematic review

Identifiers

PMID41833852
PMCPMC13496257

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.