Evidence map›Paper›PMID 41834598›Full record

ArticleProblemy endokrinologii2026

[Pheochromocytoma in Neurofibromatosis Type 1].

D V Rebrova, O I Loginova, S L Nepomnyashchaya, A R Bakhtiyarova, V F Rusakov, L M Krasnov, E A Fedorov, I K Chinchuk, Sh Sh Shikhmagomedov, E N Imyanitov and 8 more

Abstract readCase ReportsEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Problemy endokrinologii, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

D V RebrovaSaint Petersburg State University, Saint Petersburg State University Hospital.
O I LoginovaSaint Petersburg State University, Saint Petersburg State University Hospital.
S L NepomnyashchayaSaint Petersburg State University, Saint Petersburg State University Hospital.
A R BakhtiyarovaSaint Petersburg State University, Saint Petersburg State University Hospital; Almazov National Medical Research Center.
V F RusakovSaint Petersburg State University, Saint Petersburg State University Hospital.
L M KrasnovSaint Petersburg State University, Saint Petersburg State University Hospital.
E A FedorovSaint Petersburg State University, Saint Petersburg State University Hospital.
I K ChinchukSaint Petersburg State University, Saint Petersburg State University Hospital.
Sh Sh ShikhmagomedovSaint Petersburg State University, Saint Petersburg State University Hospital.
E N ImyanitovNational Medical Research Center of Oncology n.a. N.N. Petrov.
O V KuleshovSaint Petersburg State University, Saint Petersburg State University Hospital.
M A AlekseevSaint Petersburg State University, Saint Petersburg State University Hospital.
T S PridvijkinaSaint Petersburg State University, Saint Petersburg State University Hospital.
T V SavelyevaSaint Petersburg State University, Saint Petersburg State University Hospital.
A A SemenovSaint Petersburg State University, Saint Petersburg State University Hospital.
E A ZgodaSaint Petersburg State University, Saint Petersburg State University Hospital.
R A ChernikovSaint Petersburg State University, Saint Petersburg State University Hospital.
I V SleptsovSaint Petersburg State University, Saint Petersburg State University Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurofibromatosis type 1 is a hereditary disease with a wide variability of clinical manifestations, from the almost complete absence of typical symptoms to a multisystem lesion of the body. One of the possible clinical manifestations of this pathology is a pheochromocytoma - a tumor of the adrenal gland with the possible development of considerable cardiovascular complications. The article describes four cases of patients with pheochromocytoma as part of familial neurofibromatosis type 1, differing in clinical course from asymptomatic form to vivid paroxysmal manifestations. At the same time, the presence and degree of arterial hypertension did not correlate with the level of metanephrines and the size of the pheochromocytoma. 3 out of 4 patients have a hereditary history of neurofibromatosis type 1. In 1 out of 4 cases, simultaneous bilateral damage to the adrenal glands was noted, while the radiation characteristics of pheochromocytomas, both with computed tomography and CT/PET with 18-FDG, differed from the "classic" ones. An objective examination with the identification of "erased" signs of neurofibromatosis type 1 made it possible to establish the diagnosis of bilateral pheochromocytoma even with questionable laboratory and imaging data. Knowledge of clinical manifestations, timely diagnosis of neurofibromatosis type 1, comprehensive treatment and subsequent regular monitoring of patients, as well as examination of blood relatives can significantly improve prognosis and survival.

Indexed as

Adrenal Gland NeoplasmsNeurofibromatosis 1PheochromocytomaAdultFemaleHumansMaleMiddle AgedTomography, X-Ray Computed

Identifiers

PMID41834598
PMCPMC12990838

What Socratic holds

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